The application of Tet repressor in prokaryotic gene regulation and expression

R Bertram, W Hillen - Microbial biotechnology, 2008 - Wiley Online Library
Inducible gene expression based upon Tet repressor (tet regulation) is a broadly applied
tool in molecular genetics. In its original environment, Tet repressor (TetR) negatively …

The innate growth bistability and fitness landscapes of antibiotic-resistant bacteria

JB Deris, M Kim, Z Zhang, H Okano, R Hermsen… - Science, 2013 - science.org
Introduction Understanding how bacteria harboring antibiotic resistance grow in the
presence of antibiotics is critical for predicting the spread and evolution of drug resistance …

[HTML][HTML] HTLV-1 alters T cells for viral persistence and transmission

A Tanaka, M Matsuoka - Frontiers in microbiology, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus to be discovered as a
causative agent of adult T-cell leukemia-lymphoma (ATL) and chronic inflammatory …

An integrative circuit–host modelling framework for predicting synthetic gene network behaviours

C Liao, AE Blanchard, T Lu - Nature microbiology, 2017 - nature.com
One fundamental challenge in synthetic biology is the lack of quantitative tools that
accurately describe and predict the behaviours of engineered gene circuits. This challenge …

A group-specific microbiological test for the detection of tetracycline residues in raw milk

J Kurittu, S Lönnberg, M Virta… - Journal of agricultural and …, 2000 - ACS Publications
The potentiality of using a luminescent Escherichia coli strain for the specific detection of
tetracycline residues in raw bovine milk was investigated. The sensor cells contain a …

An efficient platform for genetic selection and screening of gene switches in Escherichia coli

N Muranaka, V Sharma, Y Nomura… - Nucleic acids …, 2009 - academic.oup.com
Engineered gene switches and circuits that can sense various biochemical and physical
signals, perform computation, and produce predictable outputs are expected to greatly …

The use of whole-cell biosensors to detect and quantify compounds or conditions affecting biological systems

LH Hansen, SJ Sørensen - Microbial ecology, 2001 - Springer
A new and promising technique in microbial ecology and environmental biology is the use of
whole-cell bacterial biosensors. This minireview describes the use of such biosensors for …

A Recombinant Escherichia coli Sensor Strain for the Detection of Tetracyclines

MT Korpela, JS Kurittu, JT Karvinen… - Analytical chemistry, 1998 - ACS Publications
A bioluminescent Escherichia coli K-12 strain for the specific detection of the tetracycline
group of antibiotics is described. A sensor plasmid, containing five genes from bacterial …

Molecular basis of tetracycline action: identification of analogs whose primary target is not the bacterial ribosome

B Rasmussen, HF Noller, G Daubresse… - Antimicrobial agents …, 1991 - Am Soc Microbiol
Tetracycline analogs fell into two classes on the basis of their mode of action. Tetracycline,
chlortetracycline, minocycline, doxycycline, and 6-demethyl-6-deoxytetracycline inhibited …

Detection and quantification of tetracyclines by whole cell biosensors

LH Hansen, SJ Sørensen - FEMS microbiology letters, 2000 - academic.oup.com
Three different mini-Tn 5 plasmids, containing a tetracycline-inducible promoter, P tet and a
regulatory gene, tetR, in operon fusions with a reporter gene system (lacZYA, luxCDABE or …