Acetyl-coenzyme A (acetyl-CoA), an essential metabolite, not only takes part in numerous
intracellular metabolic processes, powers the tricarboxylic acid cycle, serves as a key hub …

γ-Glutamyl moiety that is attached to the cysteine (Cys) residue in glutathione (GSH) protects
it from peptidase-mediated degradation. The sulfhydryl group of the Cys residue represents …

The molecular mechanisms connecting cellular metabolism with differentiation remain
poorly understood. Here, we find that metabolic signals contribute to stem cell differentiation …

Coenzyme A (CoA) is a vital and ubiquitous cofactor required in a vast number of enzymatic
reactions and cellular processes. To date, four rare human inborn errors of CoA biosynthesis …

Highlights•The exact functional role of NAA in metabolism is unclear.•NAA substantially
impacts cellular signaling.•Elevated NAA levels influence tumor–macrophage …

Wuwei Shexiang Pill (WSP) is a Tibetan traditional medicine, which has been demonstrated
to exhibit potent anti-inflammatory and anti-gout effects. However, the specific …

Coenzyme A (CoA) is an essential cofactor in all living cells which plays critical role in
cellular metabolism, the regulation of gene expression and the biosynthesis of major cellular …

An alcohol-induced liver injury model was induced in C57BL/6 mice to assess the protective
efficacy of Enteromorpha prolifera polysaccharides (EP) against liver damage. Histological …

The classic ketogenic diet is an effective treatment option for drug-resistant epilepsy, but its
high fat content challenges patient compliance. Optimizing liver ketone production guided by …

Climate change-induced environmental stresses pose significant challenges to plant
survival and agricultural productivity. In response, many plants undergo genetic …