Common ADRB2 Haplotypes Derived from 26 Polymorphic Sites Direct β2-Adrenergic Receptor Expression and Regulation Phenotypes
A Panebra, WC Wang, MM Malone, DRG Pitter… - PLoS …, 2010 - journals.plos.org
Background The β2-adrenergic receptor (β2AR) is expressed on numerous cell-types
including airway smooth muscle cells and cardiomyocytes. Drugs (agonists or antagonists) …
including airway smooth muscle cells and cardiomyocytes. Drugs (agonists or antagonists) …
Variable-length poly-C tract polymorphisms of the β2-adrenergic receptor 3′-UTR alter expression and agonist regulation
A Panebra, MR Schwarb, SM Swift… - … of Physiology-Lung …, 2008 - journals.physiology.org
β2-Adrenergic receptors (β2-AR) expressed on airway epithelial and smooth muscle cells
regulate mucociliary clearance and relaxation and are the targets for β-agonists in the …
regulate mucociliary clearance and relaxation and are the targets for β-agonists in the …
Allele-Specific Binding of Airway Nuclear Extracts to Polymorphic β2-Adrenergic Receptor 5′ Sequence
A Panebra, MR Schwarb, CB Glinka… - American journal of …, 2007 - atsjournals.org
Like other intronless G protein–coupled receptor genes, the β2-adrenergic receptor (β2AR)
has minimal genetic space for population variability, and has attained such via multiple …
has minimal genetic space for population variability, and has attained such via multiple …