Taxane-antibody conjugates afford potent cytotoxicity, enhanced solubility, and tumor target selectivity

V Guillemard, HU Saragovi - Cancer research, 2001 - AACR
Paclitaxel (Taxol) is a chemotherapeutic agent that prevents disassembly of microtubular
polymers, causing a growth arrest in the G2-M phase of the cell cycle and leading to …

Tumor specific novel taxoid-monoclonal antibody conjugates

X Wu, I Ojima - Current medicinal chemistry, 2004 - ingentaconnect.com
The basic principle of the targeted delivery approach is that the conjugation of a drug to a
tumorspecific molecule renders the drug inactive until it reaches the target site. Monoclonal …

Novel high molecular weight albumin-conjugated angiotensin II activates β-arrestin and G-protein pathways

HW Pang, A Linares, L Couling, J Santollo, L Ancheta… - Endocrine, 2019 - Springer
Purpose To study the ability of a novel bovine serum albumin-angiotensin II (BSA-Ang II)
conjugate to effect responses of the AT 1 angiotensin II receptor subtype mediated by the G …

[PDF][PDF] Assembly and characterization of a cell-particle hybrid system as a potential cancer vaccine

KK Ahmed - 2013 - iro.uiowa.edu
Cancer vaccines represent a promising treatment modality for a world-wide health problem.
Whether as an adjuvant or as a stand-alone therapy, cancer vaccines represent a tumor …

Immuno-DNA-directed Assembly of Heterotypic Multicellular Systems

A Shomorony, R Fan - Chemistry Letters, 2013 - academic.oup.com
An immuno-DNA-directed assembly technique based on bifunctional conjugates of uniquely
designed-ssDNA codes and antibodies specific to cell surface receptors enables rapid …