Remarkable progress has been made in the development of new therapies for cancer,
dramatically changing the landscape of treatment approaches for several malignancies and …

The cardiovascular system is affected broadly by severe acute respiratory syndrome
coronavirus 2 infection. Both direct viral infection and indirect injury resulting from …

Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …

A close and intriguing relationship has been suggested between heart failure (HF) and
coronavirus disease 2019 (COVID-19). First, COVID-19 pandemic represented a global …

Clinical application of doxorubicin (DOX), an anthracycline antibiotic with potent anti-tumor
effects, is limited because of its cardiotoxicity. However, its pathogenesis is still not entirely …

Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer with no efficacious treatment.
The application of nanomedicine is expected to bring new hope to PDAC treatment. In this …

Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic
(Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S …

Cardiovascular diseases (CVDs) are considered as the major reason for mortality and
morbidity worldwide. Substantial evidence suggests that increased oxidative stress plays a …

Dilated cardiomyopathy (DCM) is a clinical diagnosis characterized by left ventricular or
biventricular dilation and impaired contraction that is not explained by abnormal loading …

Doxorubicin is a commonly used chemotherapeutic agent for the treatment of a range of
cancers, but despite its success in improving cancer survival rates, doxorubicin is cardiotoxic …