Advances in technology have allowed for the sensitive, specific, and simultaneous
quantitative profiling of steroid precursors, bioactive steroids and inactive metabolites …

Hormones are largely responsible for the integrated communication of several physiological
systems responsible for modulating cellular growth and development. Although the specific …

Obesity is a multifaceted chronic condition with several contributing causes, including
biological risk factors, socioeconomic status, health literacy, and numerous environmental …

The synthesis and secretion of cortisol are controlled by the hypothalamic–pituitary–adrenal
axis. Cortisol exhibits a proper 24-h circadian rhythm that affects the brain, the autonomic …

Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …

Despite a complex relationship between mood, sleep and rhythm, the impact of circadian
disruptions on bipolar disorder (BD) has not been clarified. The purpose of this systematic …

In clinical trials, biochemical markers provide useful information on the drug's mode of
action, therapeutic response and side effect monitoring and can act as surrogate endpoints …

Mostly known as “the stress hormone”, cortisol has many essential functions in humans due
to its involvement in regulation of blood pressure, immune system, metabolism of protein …

Wearable sweat biosensors offer compelling opportunities for improved personal health
monitoring and non-invasive measurements of key biomarkers. Inexpensive device …

Chronic glucocorticoid (GC) treatment represents a widely-prescribed therapy for several
diseases in consideration of both anti-inflammatory and immunosuppressive activity but, if …