miR-140-5p in small extracellular vesicles from human papilla cells stimulates hair growth by promoting proliferation of outer root sheath and hair matrix cells

Y Chen, J Huang, Z Liu, R Chen, D Fu… - Frontiers in Cell and …, 2020 - frontiersin.org
The application of dermal papilla cells to hair follicle (HF) regeneration has attracted a great
deal of attention. However, cultured dermal papilla cells (DPCs) tend to lose their capacity to …

Confocal microscopy analysis reveals that only a small proportion of extracellular vesicles are successfully labelled with commonly utilised staining methods

GE Melling, R Conlon, P Pantazi, ER Dellar… - Scientific Reports, 2022 - nature.com
Assessing genuine extracellular vesicle (EV) uptake is crucial for understanding the
functional roles of EVs. This study measured the bona fide labelling of EVs utilising two …

Ectosomes and exosomes modulate neuronal spontaneous activity

IC Brás, MH Khani, D Riedel, I Parfentev, E Gerhardt… - Journal of …, 2022 - Elsevier
Extracellular vesicles (EVs) are important mediators in intercellular communication.
However, understanding the biological origin and functional effects of EVs subtypes has …

Extracellular vesicles from seminal plasma interact with T cells in vitro and drive their differentiation into regulatory T‐cells

X Zhang, PF Greve, TTN Minh… - Journal of …, 2024 - Wiley Online Library
Seminal plasma induces immune tolerance towards paternal allogenic antigens within the
female reproductive tract and during foetal development. Recent evidence suggests a role …

[HTML][HTML] Emerging chemical engineering of exosomes as “bioscaffolds” in diagnostics and therapeutics

J Wang, M Wang, N Jiang, S Ding, Q Peng, L Zheng - Genes & Diseases, 2023 - Elsevier
All cells release extracellular vesicles (EVs) as part of their normal physiology. As one of the
subtypes, exosomes (EXOs) have an average size range of approximately 40 nm–160 nm in …

Bioengineering exosomes for treatment of organ ischemia-reperfusion injury

R Toghiani, SS Abolmaali, H Najafi, AM Tamaddon - Life Sciences, 2022 - Elsevier
Abstract Ischemia-reperfusion (I/R) injury is a leading cause of death worldwide. It arises
from blood reflowing after tissue hypoxia induced by ischemia that causes severe damages …

A universal method to analyze cellular internalization mechanisms via endocytosis without non‐specific cross‐effects

M Itagaki, Y Nasu, C Sugiyama, I Nakase… - The FASEB …, 2023 - Wiley Online Library
Endocytosis is an essential biological process for nutrient absorption and intercellular
communication; it can also be used to accelerate the cellular internalization of drug delivery …

Covalently labeled fluorescent exosomes for in vitro and in vivo applications

MI González, M González-Arjona, A Santos-Coquillat… - Biomedicines, 2021 - mdpi.com
The vertiginous increase in the use of extracellular vesicles and especially exosomes for
therapeutic applications highlights the necessity of advanced techniques for gaining a …

Nanotherapeutics for prostate cancer treatment: A comprehensive review

R Hu, J Lan, D Zhang, W Shen - Biomaterials, 2024 - Elsevier
Prostate cancer (PCa) is the most prevalent solid organ malignancy and seriously affects
male health. The adverse effects of prostate cancer therapeutics can cause secondary …

Reporter systems for assessments of extracellular vesicle transfer

C Han, G Qin - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Extracellular vesicles (EVs) are lipid bilayer particles naturally released from most if not all
cell types to mediate inter-cellular exchange of bioactive molecules. Mounting evidence …