Recent developments in drug discovery for leishmaniasis and human African trypanosomiasis

AS Nagle, S Khare, AB Kumar, F Supek… - Chemical …, 2014 - ACS Publications
Leishmaniasis is a parasitic disease that presents four main clinical syndromes: cutaneous
leishmaniasis (CL), mucocutaneous leishmaniasis (MCL), visceral leishmaniasis/kala azar …

[HTML][HTML] A decade bibliometric analysis of global research on leishmaniasis in Web of Science database

M Soosaraei, AA Khasseh, M Fakhar… - Annals of medicine and …, 2018 - Elsevier
Background Leishmaniasis is an extremely relevant tropical disease, with global distribution.
It still remains a main public health concern in low-income countries, and it is necessary to …

Human leishmaniasis in Brazil: A general review

L Anversa, MGS Tiburcio, VB Richini-Pereira… - Revista da Associação …, 2018 - SciELO Brasil
Leishmaniasis is a disease with ample clinical spectrum and epidemiological diversity and
is considered a major public health problem. This article presents an overview of the …

Laboratory diagnosis of cutaneous and visceral leishmaniasis: current and future methods

JQ Reimão, EM Coser, MR Lee, AC Coelho - Microorganisms, 2020 - mdpi.com
Leishmaniasis is a neglected tropical disease with two main clinical forms: cutaneous and
visceral leishmaniasis. Diagnosis of leishmaniasis is still a challenge, concerning the …

Laboratory diagnostics for human Leishmania infections: a polymerase chain reaction-focussed review of detection and identification methods

I Gow, NC Smith, D Stark, J Ellis - Parasites & Vectors, 2022 - Springer
Leishmania infections span a range of clinical syndromes and impact humans from many
geographic foci, but primarily the world's poorest regions. Transmitted by the bite of a female …

The pathogenicity and virulence of Leishmania-interplay of virulence factors with host defenses

AK Gupta, S Das, M Kamran, SA Ejazi, N Ali - Virulence, 2022 - Taylor & Francis
Leishmaniasis is a group of disease caused by the intracellular protozoan parasite of the
genus Leishmania. Infection by different species of Leishmania results in various host …

Developments in diagnosis of visceral leishmaniasis in the elimination era

OP Singh, S Sundar - Journal of parasitology research, 2015 - Wiley Online Library
Visceral leishmaniasis (VL) is the most devastating parasitic infection worldwide causing
high morbidity and mortality. Clinical presentation of VL ranges from asymptomatic or …

Application of dendrimers for the treatment of infectious diseases

Z Mhlwatika, BA Aderibigbe - Molecules, 2018 - mdpi.com
Dendrimers are drug delivery systems that are characterized by a three-dimensional, star-
shaped, branched macromolecular network. They possess ideal properties such as low …

Developments in treatment methodologies using dendrimers for infectious diseases

N Filipczak, SSK Yalamarty, X Li, F Parveen… - Molecules, 2021 - mdpi.com
Dendrimers comprise a specific group of macromolecules, which combine structural
properties of both single molecules and long expanded polymers. The three-dimensional …

Visceral leishmaniasis in Southwestern Iran: a retrospective clinico-hematological analysis of 380 consecutive hospitalized cases (1999–2014)

B Sarkari, T Naraki, MA Ghatee, S Abdolahi Khabisi… - PloS one, 2016 - journals.plos.org
Visceral Leishmaniasis (VL) is an endemic parasitic disease and remains as a major health
concern in southwestern Iran. The current study describes clinico-hematological …