Left ventricular remodeling after myocardial infarction: from physiopathology to treatment

SA Leancă, D Crișu, AO Petriș, I Afrăsânie, A Genes… - Life, 2022 - mdpi.com
Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …

[HTML][HTML] Melatonin as a therapeutic agent for alleviating endothelial dysfunction in cardiovascular diseases: Emphasis on oxidative stress

X Zhang, Y Zheng, Z Wang, J Gan, B Yu, B Lu… - Biomedicine & …, 2023 - Elsevier
The vascular endothelium is vital in maintaining cardiovascular health by regulating
vascular permeability and tone, preventing thrombosis, and controlling vascular …

Tryptophan: from diet to cardiovascular diseases

NJ Melhem, S Taleb - International Journal of Molecular Sciences, 2021 - mdpi.com
Cardiovascular disease (CVD) is one of the major causes of mortality worldwide.
Inflammation is the underlying common mechanism involved in CVD. It has been recently …

Pharmacological modulation of cardiac remodeling after myocardial infarction

W Zhao, J Zhao, J Rong - Oxidative Medicine and Cellular …, 2020 - Wiley Online Library
Cardiac remodeling describes a series of structural and functional changes in the heart after
myocardial infarction (MI). Adverse post‐MI cardiac remodeling directly jeopardizes the …

Role of the antioxidant activity of melatonin in myocardial ischemia-reperfusion injury

JL Bermudez-Gonzalez, D Sanchez-Quintero… - Antioxidants, 2022 - mdpi.com
Ischemia-reperfusion injury is a common problem in the age of interventional cardiology; it is
primarily mediated by oxidative stress and reactive agents. Melatonin has antioxidative …

[HTML][HTML] Melatonin as a potential treatment for septic cardiomyopathy

AM Taha, AM Mahmoud, MM Ghonaim… - Biomedicine & …, 2023 - Elsevier
Septic cardiomyopathy (SCM) is a common complication of sepsis contributing to high
mortality rates. Its pathophysiology involves complex factors, including inflammatory …

Melatonin ameliorates myocardial infarction in obese diabetic individuals: the possible involvement of macrophage apoptotic factors

J Maity, T Dey, A Banerjee… - Journal of Pineal …, 2023 - Wiley Online Library
In recent days, the hike in obesity‐mediated epidemics across the globe and the prevalence
of obesity‐induced cardiovascular disease has become one of the chief grounds for …

[HTML][HTML] Gasdermin D-mediated pyroptosis in myocardial ischemia and reperfusion injury: Cumulative evidence for future cardioprotective strategies

P Yanpiset, C Maneechote, S Sriwichaiin… - … Pharmaceutica Sinica B, 2023 - Elsevier
Cardiomyocyte death is one of the major mechanisms contributing to the development of
myocardial infarction (MI) and myocardial ischemia/reperfusion (MI/R) injury. Due to the …

Melatonin can modulate neurodegenerative diseases by regulating endoplasmic reticulum stress

YM Yoo, SS Joo - International Journal of Molecular Sciences, 2023 - mdpi.com
As people age, their risks of developing degenerative diseases such as cancer, diabetes,
Parkinson's Disease (PD), Alzheimer's Disease (AD), rheumatoid arthritis, and osteoporosis …

Insights into research on myocardial ischemia/reperfusion injury from 2012 to 2021: a bibliometric analysis

M Bai, J Zhang, D Chen, M Lu, J Li, Z Zhang… - European Journal of …, 2023 - Springer
Background Numerous studies on myocardial ischemia/reperfusion (MI/R) injury have been
undertaken in recent years. Hotspots and developmental trends in MI/R research are being …