System and method for pathogen detection and identification

M Wagner, J Heanue - US Patent 8,981,298, 2015 - Google Patents
This disclosure concerns a pathogen inspection system that includes a handling system that
presents single cells from a sample to at least one QCL laser source. The QCL laser source …

Molecular monitoring of glioblastoma's immunogenicity using a combination of Raman spectroscopy and chemometrics

C Robert, J Tsiampali, SJ Fraser-Miller… - … Acta Part A: Molecular …, 2021 - Elsevier
Raman spectroscopy (RS) has been used as a powerful diagnostic and non-invasive tool in
cancer diagnosis as well as in discrimination of cancer and immune cells. In this study RS in …

Subcellular spectroscopic markers, topography and nanomechanics of human lung cancer and breast cancer cells examined by combined confocal Raman …

GD McEwen, Y Wu, M Tang, X Qi, Z Xiao, SM Baker… - Analyst, 2013 - pubs.rsc.org
The nanostructures and hydrophobic properties of cancer cell membranes are important for
membrane fusion and cell adhesion. They are directly related to cancer cell biophysical …

Label-free Raman imaging of live osteosarcoma cells with multivariate analysis

J Li, J Qin, X Zhang, R Wang, Z Liang, Q He… - Applied microbiology …, 2019 - Springer
Confocal Raman microspectral imaging (CRMI) is an advanced cell-imaging method that
maps endogenous molecular compositions with their unique spectral fingerprint indicators …

Raman spectroscopic identification of single bacterial cells at different stages of their lifecycle

MM Hlaing, M Dunn, PR Stoddart, SL McArthur - Vibrational Spectroscopy, 2016 - Elsevier
Early, rapid, and reliable bacterial identification is of great importance in natural
environments and in medical situations. Numerous studies have shown that Raman …

[HTML][HTML] Chick sexing based on the blood analysis using Raman spectroscopy

S Matsumoto, A Ogino, K Onoe, J Ukon, M Ishigaki - Scientific Reports, 2024 - nature.com
Efforts are underway to develop technology for automatically determining the sex of chick
embryos, aimed at establishing a stable and efficient poultry farming system while also …

A single-organelle optical omics platform for cell science and biomarker discovery

A Pliss, AN Kuzmin, A Lita, R Kumar, O Celiku… - Analytical …, 2021 - ACS Publications
Research in fundamental cell biology and pathology could be revolutionized by developing
the capacity for quantitative molecular analysis of subcellular structures. To that end, we …

Protective effects of melatonin against oxidative stress in flow cytometry‐sorted buffalo sperm

XX Li, XG Yang, YQ Lu, SS Lu, M Zhang… - … in domestic animals, 2012 - Wiley Online Library
Contents Previous reports of the ability of melatonin to scavenge a variety of toxic oxygen
and nitrogen‐based reactants suggest that melatonin could be an effective antioxidant for …

A Rapid and Label‐free SERS Detection Method for Biomarkers in Clinical Biofluids

KV Kong, WK Leong, Z Lam, T Gong, D Goh, WKO Lau… - Small, 2014 - Wiley Online Library
As indicators of physiological conditions, the monitoring of biomarkers holds great promise
as clinical diagnostics to facilitate successful treatment of diseases and the improvement of …

Time fluctuations and imaging in the SERS spectra of fungal hypha grown on nanostructured substrates

A Szeghalmi, S Kaminskyj, P Rösch… - The Journal of …, 2007 - ACS Publications
Surface-enhanced Raman scattering (SERS) spectroscopy is an emerging technique in
biomolecular analysis that can have a tremendous impact in the life sciences. We report on …