Combining pharmacokinetics and vibrational spectroscopy: MCR-ALS hard-and-soft modelling of drug uptake in vitro using tailored kinetic constraints

D Pérez-Guaita, G Quintás, Z Farhane, R Tauler… - Cells, 2022 - mdpi.com
Raman microspectroscopy is a label-free technique which is very suited for the investigation
of pharmacokinetics of cellular uptake, mechanisms of interaction, and efficacies of drugs in …

Computer assisted optical screening of human ovarian cancer using Raman spectroscopy

I Ullah, I Ahmad, H Nisar, S Khan, R Ullah… - Photodiagnosis and …, 2016 - Elsevier
Conventional screening tools for ovarian cancer such as cancer antigen (CA-125) and trans-
pelvic ultrasound have poor sensitivity and specificity, indicating the need for better and …

Vibrational spectroscopy: disease diagnostics and beyond

HJ Byrne, KM Ostrowska, H Nawaz, J Dorney… - … methods in biology and …, 2014 - Springer
This chapter outlines some developments in the applications of vibrational spectroscopy for
disease diagnostics and demonstrates how the applications of the spectroscopic techniques …

Hybrid Rayleigh, Raman and two‐photon excited fluorescence spectral confocal microscopy of living cells

VV Pully, A Lenferink, C Otto - Journal of Raman Spectroscopy, 2010 - Wiley Online Library
A hybrid fluorescence–Raman confocal microscopy platform is presented, which integrates
low‐wavenumber‐resolution Raman imaging, Rayleigh scatter imaging and two‐photon …

Label-free rapid identification of tumor cells and blood cells with silver film SERS substrate

YJ Zhang, QY Zeng, LF Li, MN Qi, QC Qi, SX Li… - Optics …, 2018 - opg.optica.org
The detection of circulating tumor cells (CTCs) from peripheral blood is considered as great
significance for the diagnosis and prognosis of cancer patients. Raman spectroscopy is a …

Label-free determination of the cell cycle phase in human embryonic stem cells by Raman microspectroscopy

SO Konorov, HG Schulze, JM Piret, MW Blades… - Analytical …, 2013 - ACS Publications
The cell cycle is a series of integrated and coordinated physiological events that results in
cell growth and replication. Besides observing the event of cell division it is not feasible to …

Plasmon waveguide resonance for tag-free selective Raman detection of biochemical composition in single-cell

S Zhou, H Sun, D Wu, R Gao, H Zhang, Z Li… - Sensors and Actuators B …, 2023 - Elsevier
Highly selective and non-radioactive Raman detection of the biochemical composition of
living single-cell is a key method of evaluating complex biological reaction processes …

Biochemical changes in lipid and protein metabolism caused by mannose-Raman spectroscopy studies

M Kopeć, K Beton-Mysur, H Abramczyk - Analyst, 2024 - pubs.rsc.org
Biochemical analysis of human normal bronchial cells (BEpiC) and human cancer lung cells
(A549) has been performed by using Raman spectroscopy and Raman imaging. Our …

Raman micro-spectroscopy analysis of human lens epithelial cells exposed to a low-dose-range of ionizing radiation

CH Allen, A Kumar, S Qutob, B Nyiri… - Physics in Medicine …, 2018 - iopscience.iop.org
Recent findings in populations exposed to ionizing radiation (IR) indicate dose-related lens
opacification occurs at much lower doses (< 2 Gy) than indicated in radiation protection …

Label-Free Human Disease Characterization through Circulating Cell-Free DNA Analysis Using Raman Spectroscopy

VM Papadakis, C Cheimonidi… - International Journal of …, 2023 - mdpi.com
Circulating cell-free DNA (ccfDNA) is a liquid biopsy biomaterial attracting significant
attention for the implementation of precision medicine diagnostics. Deeper knowledge …