Surface-enhanced Raman scattering based nonfluorescent probe for multiplex DNA detection

L Sun, C Yu, J Irudayaraj - Analytical Chemistry, 2007 - ACS Publications
To provide rapid and accurate detection of DNA markers in a straightforward, inexpensive,
and multiplex format, an alternative surface-enhanced Raman scattering based probe was …

Raman microspectroscopy for non-invasive biochemical analysis of single cells

RJ Swain, MM Stevens - Biochemical Society Transactions, 2007 - portlandpress.com
Recent developments in biomedical vibrational spectroscopy now permit the non-invasive
imaging of cells and tissues within both the laboratory and clinical settings. The rapid nature …

Simultaneous fingerprint and high‐wavenumber fiber‐optic Raman spectroscopy enhances real‐time in vivo diagnosis of adenomatous polyps during colonoscopy

MS Bergholt, K Lin, J Wang, W Zheng… - Journal of …, 2016 - Wiley Online Library
Colorectal cancer can be prevented if detected early (eg, precancerous polyps‐adenoma).
Endoscopic differential diagnosis of hyperplastic polyps (that have little or no risk of …

Full range characterization of the Raman spectra of organs in a murine model

N Huang, M Short, J Zhao, H Wang, H Lui… - Optics express, 2011 - opg.optica.org
Raman spectroscopy is a minimally-invasive optical technique with great potential for in vivo
cancer detection and disease diagnosis. However, there is no systematic study of the …

Identification and differentiation of single cells from peripheral blood by Raman spectroscopic imaging

U Neugebauer, JH Clement, T Bocklitz… - Journal of …, 2010 - Wiley Online Library
Medical diagnosis can be improved significantly by fast, highly sensitive and quantitative cell
identification from easily accessible body fluids. Prominent examples are disseminated …

System for identifying and sorting living cells

M Wagner, J Heanue - US Patent 8,941,062, 2015 - Google Patents
In embodiments of the present invention, a system and method of cytometry may include
presenting a single sperm cell to at least one laser source configured to deliver light to the …

IR microspectroscopy: potential applications in cervical cancer screening

MJ Walsh, MJ German, M Singh, HM Pollock… - Cancer letters, 2007 - Elsevier
Screening exfoliative cytology for early dysplastic cells reduces incidence and mortality from
squamous carcinoma of the cervix. In the developed world, screening programmes have …

Raman imaging at biological interfaces: applications in breast cancer diagnosis

J Surmacki, J Musial, R Kordek, H Abramczyk - Molecular cancer, 2013 - Springer
Background One of the most important areas of Raman medical diagnostics is identification
and characterization of cancerous and noncancerous tissues. The methods based on …

In vivo Raman spectroscopy in the diagnostics of colon cancer

M Fousková, J Vališ, A Synytsya, L Habartová, J Petrtýl… - Analyst, 2023 - pubs.rsc.org
Early detection and accurate diagnosis of colorectal carcinoma are crucial for successful
treatment, yet current methods can be invasive and even inaccurate in some cases. In this …

A robust method for automated background subtraction of tissue fluorescence

A Cao, AK Pandya, GK Serhatkulu… - Journal of Raman …, 2007 - Wiley Online Library
This paper introduces a new robust method for the removal of background tissue
fluorescence from Raman spectra. Raman spectra consist of noise, fluorescence and …