A reliable Raman-spectroscopy-based approach for diagnosis, classification and follow-up of B-cell acute lymphoblastic leukemia

S Managò, C Valente, P Mirabelli, D Circolo, F Basile… - Scientific reports, 2016 - nature.com
Acute lymphoblastic leukemia type B (B-ALL) is a neoplastic disorder that shows high
mortality rates due to immature lymphocyte B-cell proliferation. B-ALL diagnosis requires …

In vivo diagnosis of gastric cancer using Raman endoscopy and ant colony optimization techniques

MS Bergholt, W Zheng, K Lin, KY Ho… - … journal of cancer, 2011 - Wiley Online Library
This study aims to evaluate the clinical utility of image‐guided Raman endoscopy for in vivo
diagnosis of neoplastic lesions in the stomach at gastroscopy. A rapid‐acquisition image …

A robust method for automated background subtraction of tissue fluorescence

A Cao, AK Pandya, GK Serhatkulu… - Journal of Raman …, 2007 - Wiley Online Library
This paper introduces a new robust method for the removal of background tissue
fluorescence from Raman spectra. Raman spectra consist of noise, fluorescence and …

Facile synthesis of gold nanohexagons on graphene templates in Raman spectroscopy for biosensing cancer and cancer stem cells

M Manikandan, HN Abdelhamid, A Talib… - Biosensors and …, 2014 - Elsevier
Several surface enhanced Raman spectroscopy (SERS) substrates were prepared based
on in situ nucleation of gold nanohexagons (Au) on graphene (G) nanosheets (Au@ G), G …

Temporal In Vitro Raman Spectroscopy for Monitoring Replication Kinetics of Epstein–Barr Virus Infection in Glial Cells

D Tiwari, S Jakhmola, DK Pathak, R Kumar, HC Jha - ACS omega, 2020 - ACS Publications
Raman spectroscopy can be used as a tool to study virus entry and pathogen-driven
manipulation of the host efficiently. To date, Epstein–Barr virus (EBV) entry and altered …

Characterizing variability in in vivo Raman spectra of different anatomical locations in the upper gastrointestinal tract toward cancer detection

MS Bergholt, W Zheng, K Lin, KY Ho… - … of biomedical optics, 2011 - spiedigitallibrary.org
Raman spectroscopy is an optical vibrational technology capable of probing biomolecular
changes of tissue associated with cancer transformation. This study aimed to characterize in …

Fiber‐optic Raman spectroscopy probes gastric carcinogenesis in vivo at endoscopy

MS Bergholt, W Zheng, KY Ho, M Teh… - Journal of …, 2013 - Wiley Online Library
Intestinal‐type gastric carcinogenesis is a complex multi‐step disease, and early precursors
(eg intestinal metaplasia (IM), dysplasia) can be very challenging to identify using …

Non‐invasive time‐course imaging of apoptotic cells by confocal Raman micro‐spectroscopy

A Zoladek, FC Pascut, P Patel… - Journal of Raman …, 2011 - Wiley Online Library
Confocal Raman micro‐spectroscopy (CRMS) was used to measure time‐course spectral
images of live cells undergoing apoptosis without using molecular labels or other invasive …

Mesoscopic characterization of prostate cancer using Raman spectroscopy: potential for diagnostics and therapeutics

K Aubertin, VQ Trinh, M Jermyn, P Baksic… - BJU …, 2018 - Wiley Online Library
Objective To test if Raman spectroscopy (RS) is an appropriate tool for the diagnosis and
possibly grading of prostate cancer (PC a). Patients and Methods Between 20 and 50 …

Variability in Raman Spectra of Single Human Tumor Cells Cultured in Vitro: Correlation with Cell Cycle and Culture Confluency

Q Matthews, A Jirasek, J Lum, X Duan… - Applied …, 2010 - opg.optica.org
In this work we investigate the capability of Raman microscopy (RM) to detect inherent
sources of biochemically based spectral variability between single cells of a human tumor …