Raman spectroscopy of single human tumour cells exposed to ionizing radiation in vitro

Q Matthews, AG Brolo, J Lum, X Duan… - Physics in Medicine & …, 2010 - iopscience.iop.org
This work investigates the capability of Raman spectroscopy (RS) to study the effects of
ionizing radiation on single human tumour cells. Prostate tumour cells (cell line DU145) are …

Nanostructured surfaces for analysis of anticancer drug and cell diagnosis based on electrochemical and SERS tools

WA El-Said, J Yoon, JW Choi - Nano Convergence, 2018 - Springer
Discovering new anticancer drugs and screening their efficacy requires a huge amount of
resources and time-consuming processes. The development of fast, sensitive, and …

Raman and infrared spectroscopy distinguishing replicative senescent from proliferating primary human fibroblast cells by detecting spectral differences mainly due to …

K Eberhardt, C Beleites, S Marthandan… - Analytical …, 2017 - ACS Publications
Cellular senescence is a terminal cell cycle arrested state, assumed to be involved in tumor
suppression. We studied four human fibroblast cell strains (BJ, MRC-5, IMR-90, and WI-38) …

Raman Spectroscopy: A Tool for Molecular Fingerprinting of Brain Cancer

S Murugappan, SAM Tofail, ND Thorat - ACS omega, 2023 - ACS Publications
Brain cancer is one of those few cancers with very high mortality and low five-year survival
rate. First and foremost reason for the woes is the difficulty in diagnosing and monitoring the …

Spectroscopic diagnosis of laryngeal carcinoma using near-infrared Raman spectroscopy and random recursive partitioning ensemble techniques

SK Teh, W Zheng, DP Lau, Z Huang - Analyst, 2009 - pubs.rsc.org
In this work, we evaluated the diagnostic ability of near-infrared (NIR) Raman spectroscopy
associated with the ensemble recursive partitioning algorithm based on random forests for …

Biochemical differences in tumorigenic and nontumorigenic cells measured by Raman and infrared spectroscopy

JR Mourant, KW Short, S Carpenter… - … of biomedical optics, 2005 - spiedigitallibrary.org
Both infrared and Raman spectroscopies have the potential to noninvasively estimate the
biochemical composition of mammalian cells, although this cannot be unambiguously …

SERS studies on normal epithelial and cancer cells derived from clinical breast cancer specimens

LSN Shen, Y Du, N Wei, Q Li, SM Li, TM Sun… - … Acta Part A: Molecular …, 2020 - Elsevier
Surface-enhanced Raman scattering (SERS) spectroscopy of single-cell suspensions
obtained from fresh specimens of breast cancer tissue and normal breast tissue by …

Single particle QCL-based mid-IR spectroscopy system with analysis of scattering

M Wagner, J Heanue - US Patent 8,502,148, 2013 - Google Patents
This disclosure concerns a system with scattering analysis including a handling system that
presents a single particle to at least one quantum cascade laser (QCL) source. The QCL …

Raman signature from brain hippocampus could aid Alzheimer's disease diagnosis

P Chen, A Shen, W Zhao, SJ Baek, H Yuan, J Hu - Applied optics, 2009 - opg.optica.org
Micro-Raman spectroscopy (MRS) is used for the first time to our knowledge to investigate
brain hippocampus tissue from Alzheimer's disease (AD) infected rats. In situ Raman …

Processing ThinPrep cervical cytological samples for Raman spectroscopic analysis

F Bonnier, D Traynor, P Kearney, C Clarke, P Knief… - Analytical …, 2014 - pubs.rsc.org
Raman microspectroscopy has been proven to be a promising technique for diagnosis and
early detection of pathologies. The data collected delivers a chemical fingerprint allowing …