We assess the clinical utility of a unique simultaneous fingerprint (FP)(ie, 800-1800 cm^− 1)
and high-wavenumber (HW)(ie, 2800-3600 cm^− 1) fiber-optic Raman spectroscopy for in …

Background Nanoparticles are potentially used for early cancer detection, accurate
diagnosis, and cancer treatment. Results In this paper, the breast cancer cells treated with …

Today highly complex 3D cell culture formats that closely mimic the in vivo situation are
increasingly available. Despite their wide use, the development of analytical methods and …

Microcalcifications are early markers of breast cancer and can provide valuable prognostic
information to support clinical decision-making. Current detection of calcifications in breast …

Three dimensional collagen gels have been used as matrices for the imaging of live cells by
Raman spectroscopy. The study is conducted on a human lung adenocarcinoma (A549) and …

Raman spectroscopy is a unique vibrational spectroscopic technique which can be used to
probe biochemicals and biomolecular structures and conformations of tissues. The main …

Circulating cell-free DNA (ccfDNA) is a liquid biopsy biomaterial attracting significant
attention for the implementation of precision medicine diagnostics. Deeper knowledge …

Nanofiber meshes holds great promise in wound healing applications by mimicking the
topography of extracellular matrix, hence providing guidance for crucial cells involved in the …

Macrophages are key cells in the immune inflammatory response that can be differentiated
into M1 and M2 phenotypes. Polarization has a critical therapeutic value, especially in …

This paper presents new biological results on ex vivo breast tissue based on Raman
spectroscopy and demonstrates its power as diagnostic tool with the key advantage in …