Simvastatin is one of the most frequently prescribed statins because of its efficacy in the
treatment of hypercholesterolemia, reducing cardiovascular risk and related mortality …

Restoring BReast cancer Metastasis Suppressor 1 (BRMS1) expression suppresses
metastasis in MDA-MB-435 human breast carcinoma cells at ectopic sites without affecting …

Fourier transform infrared microspectroscopy (FTIR-MSP) is potentially a powerful analytical
method for identifying the spectral properties of biological activity in cells. The goal of the …

Raman spectroscopy on single, living epithelial cells captured in a laser trap is shown to
have diagnostic power over colorectal cancer. This new single-cell technology comprises …

Intracellular distribution of doxorubicin (DOX) and its squalenoylated (SQ-DOX)
nanoparticles (NPs) form in murine lung carcinoma M109 and human breast carcinoma …

As biospectroscopy techniques continue to be developed for screening or diagnosis within a
point-of-care setting, an important development for this field will be high-throughput …

For oral cancers, screening and monitoring of high-risk populations can aid in early
diagnosis and improve overall outcomes. Of the new methods, approaches based on …

Fixation of biological sample is an essential technique applied in order to “freeze” in time the
intracellular molecular content. However, fixation induces changes of the cellular molecular …

Large-scale intracellular signaling during developmental growth or in response to
environmental alterations are largely orchestrated by chromatin within the cell nuclei …

We report on a cell-based biosensor application that utilizes patterned single-cell arrays
combined with confocal Raman spectroscopy to observe the time-dependent drug response …