The high pace of gene discovery has resulted in thrilling advances in the field of epilepsy
genetics. Clinical testing with comprehensive gene panels, exomes, or genomes are now …

Abstract The International League Against Epilepsy (ILAE) Task Force on Nosology and
Definitions proposes a classification and definition of epilepsy syndromes in the neonate …

Objective This study was undertaken to gain consensus from experienced physicians and
caregivers regarding optimal diagnosis and management of Dravet syndrome (DS), in the …

Dravet syndrome (DS) and Lennox–Gastaut syndrome (LGS) are rare developmental and
epileptic encephalopathies associated with seizure and nonseizure symptoms. A …

Background and Objectives We aimed to determine the population-based cumulative
incidence and prevalence of developmental and epileptic encephalopathies (DEEs) and …

Bottom-of-sulcus dysplasia (BOSD) is increasingly recognized as a cause of drug-resistant,
surgically-remediable, focal epilepsy, often in seemingly MRI-negative patients. We describe …

Background The developmental and epileptic encephalopathies (DEEs) are the most severe
group of epilepsies which co-present with developmental delay and intellectual disability …

Developmental and epileptic encephalopathies (DEE) are a group of disorders associated
with intractable seizures, brain development, and functional abnormalities, and in some …

Aim To explore the relationship between social care‐related quality of life (SCrQoL) for
caregivers of a child with a developmental and epileptic encephalopathy (DEE; such as …

Aim To assess the clinical utility of exome sequencing for patients with developmental and
epileptic encephalopathies (DEEs). Method Over 2 years, patients with DEEs were recruited …