Inborn errors of immunity (IEI) are genetic disorders with extensive clinical presentations.
They can range from increased susceptibility to infections to significant immune …

Inborn errors of immunity (IEIs) or primary immunodeficiency diseases, are disorders caused
by genetic defects affecting immune function. Clinically, IEI presents mainly as recurrent or …

Primary immunodeficiency disorders (PIDs) are inborn errors of immunity (IEI) that cause
immune system impairment. To date, more than 400 single-gene IEI have been well defined …

Abstract Background Mendelian Susceptibility to Mycobacterial Disease (MSMD) is a
primary immunodeficiency (PID) characterised by a predisposition to infection by weakly …

Inborn errors of immunity (IEI) are inherited monogenic disorders resulting in defective
immune response. Non‐infectious presentations are increasingly more apparent. Widely …

Immune response to tuberculosis (TB) has been extensively studied in the past decades and
classically involves cellular immunity. However, evidence suggests that humoral immunity …

Background. Tuberculosis (TB) is a serious chronic bacterial infection caused by
Mycobacterium tuberculosis (MTB). It is one of the deadliest diseases in the world and a …

The diagnosis and treatment of patients with mendelian susceptibility to mycobacterial
disease (MSMD) pose consistent challenges due to the diverse infection spectrum observed …

Background Severe infections in the absence of secondary immunodeficiency can alert
clinicians to single-gene inborn errors of immunity/primary immunodeficiency disorders …

Diagnosis of primary immunodeficiency diseases in the develo... : Current Opinion in Pediatrics
Diagnosis of primary immunodeficiency diseases in the developing world: the need for …