[HTML][HTML] Barriers and strategies of cationic liposomes for cancer gene therapy

C Liu, L Zhang, W Zhu, R Guo, H Sun, X Chen… - … Therapy Methods & …, 2020 - cell.com
Cationic liposomes (CLs) have been regarded as the most promising gene delivery vectors
for decades with the advantages of excellent biodegradability, biocompatibility, and high …

Protein corona: Friend or foe? Co-opting serum proteins for nanoparticle delivery

W Kim, NK Ly, Y He, Y Li, Z Yuan, Y Yeo - Advanced drug delivery reviews, 2023 - Elsevier
For systemically delivered nanoparticles to reach target tissues, they must first circulate long
enough to reach the target and extravasate there. A challenge is that the particles end up …

Influence of surface chemistry and morphology of nanoparticles on protein corona formation

R Bilardo, F Traldi, A Vdovchenko… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Nanomaterials offer promising solutions as drug delivery systems and imaging agents in
response to the demand for better therapeutics and diagnostics. However, the limited …

The interplay between PEGylated nanoparticles and blood immune system

C Guo, H Yuan, Y Wang, Y Feng, Y Zhang, T Yin… - Advanced Drug Delivery …, 2023 - Elsevier
During the last two decades, an increasing number of reports have pointed out that the
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …

Biocompatibility of nanomaterials and their immunological properties

TR Kyriakides, A Raj, TH Tseng, H Xiao… - Biomedical …, 2021 - iopscience.iop.org
Nanomaterials (NMs) have revolutionized multiple aspects of medicine by enabling novel
sensing, diagnostic, and therapeutic approaches. Advancements in processing and …

[HTML][HTML] Understanding the bidirectional interactions between two-dimensional materials, microorganisms, and the immune system

G Peng, B Fadeel - Advanced drug delivery reviews, 2022 - Elsevier
Abstract Two-dimensional (2D) materials such as the graphene-based materials, transition
metal dichalcogenides, transition metal carbides and nitrides (MXenes), black phosphorus …

The role of protein corona on nanodrugs for organ-targeting and its prospects of application

S Wang, J Zhang, H Zhou, YC Lu, X Jin, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …

Artificial engineering of the protein corona at bio-nano interfaces for improved cancer-targeted nanotherapy

S Khan, M Sharifi, JP Gleghorn, MMN Babadaei… - Journal of Controlled …, 2022 - Elsevier
Nanoparticles (NPs) have been used in numerous applications as anticancer, antibacterial
and antioxidant agents. Artificial engineering of protein interactions with NPs in biological …

The Janus of Protein Corona on nanoparticles for tumor targeting, immunotherapy and diagnosis

X Wang, W Zhang - Journal of Controlled Release, 2022 - Elsevier
The therapeutics based on nanoparticles (NPs) are considered as the promising strategy for
tumor detection and treatment. However, one of the most challenges is the adsorption of …

[HTML][HTML] Nanoparticles surface chemistry influence on protein corona composition and inflammatory responses

LE González-García, MN MacGregor, RM Visalakshan… - Nanomaterials, 2022 - mdpi.com
Nanoparticles are widely used for biomedical applications such as vaccine, drug delivery,
diagnostics, and therapeutics. This study aims to reveal the influence of nanoparticle surface …