Transient receptor potential vanilloid subtype 3 (TRPV3) is an ion channel with a sensory
function that is most abundantly expressed in keratinocytes and peripheral neurons. TRPV3 …

Atopic dermatitis (AD) is an inflammatory skin disease characterized by intense pruritus. AD
is harmful to both children and adults, but its pathogenic mechanism has yet to be fully …

Itching is a sensory phenomenon characterized by an unpleasant sensation that makes you
want to scratch the skin, and chronic itching diminishes the quality of life. In recent studies …

Renal fibrosis is a global health concern with limited curative treatment. Canonical transient
receptor potential channel 6 (TRPC6), a nonselective cation channel, has been shown to …

Pruritus is defined as an unpleasant sensation that elicits a desire to scratch. Nearly a third
of the world's population may suffer from pruritus during their lifetime. This symptom is widely …

In parallel with a steady rise in cancer incidence worldwide, the scientific community is
increasingly focused on finding novel, safer and more efficient modalities for managing this …

A topic dermatitis (AD) is a common chronic and recurrent skin disorder. The protective
effects of sodium butyrate (NaB), a metabolite of short-chain fatty acid breakdown by the gut …

Abstract Background Flowers of Abelmoschus manihot (L.) medic (AM) is a traditional
Chinese medicine used to treat chronic nephritis, nephrotic syndrome, diabetic nephropathy …

Acne is a common chronic inflammatory disease of the pilosebaceous unit. Transient
receptor potential vanilloid 3 (TRPV3) is an ion channel that is involved in inflammatory …

Chronic itch is a debilitating condition with limited treatment options, severely affecting
quality of life. The identification of pruriceptors has sparked a growing interest in the …