Extensive use of chemical insecticides adversely affects both environment and human
health. One of the most popular biological pest control alternatives is bioinsecticides based …

The correct wiring of neuronal circuits depends on outgrowth and guidance of neuronal
processes during development. In the past two decades, great progress has been made in …

Chronic inflammation predisposes to aging-associated disease, but it is unknown whether
immunity regulation might be important for extending healthy lifespan. Here we show that in …

Impairment of ribosome function activates the MAPKKK ZAK, leading to activation of mitogen-
activated protein (MAP) kinases p38 and JNK and inflammatory signaling. The mechanistic …

Natural antioxidants have recently emerged as a highly exciting and significant topic in anti-
aging research. Diverse organism models present a viable protocol for future research …

Aging, genomic stress, and mitochondrial dysfunction are risk factors for neurodegenerative
pathologies, such as Parkinson disease (PD). Although genomic instability is associated …

Cadmium is an environmental pollutant and significant health hazard that is similar to the
physiological metal zinc. In Caenorhabditis elegans, high zinc homeostasis is regulated by …

Insulin signaling pathway is conserved and important during the control of biological
processes in organisms. In this study, using the simulated microgravity system in …

The in vivo function of p38 mitogen-activated protein kinase (MAPK) signaling in regulating
the response to simulated microgravity is still largely unclear. Using Caenorhabditis elegans …

In Caenorhabditis elegans, ROS generated in response to intestinal infection induces SKN-
1, a protective transcription factor homologous to nuclear factor erythroid 2-related factor 1 or …