[HTML][HTML] Galectin-1 in obesity and type 2 diabetes
E Fryk, VRR Silva, PA Jansson - Metabolites, 2022 - mdpi.com
Galectin-1 is a carbohydrate-binding protein expressed in many tissues. In recent years,
increasing evidence has emerged for the role of galectin-1 in obesity, insulin resistance and …
increasing evidence has emerged for the role of galectin-1 in obesity, insulin resistance and …
Omics and cardiometabolic disease risk prediction
UA Tahir, RE Gerszten - Annual review of medicine, 2020 - annualreviews.org
Risk assessments are integral for the prevention and management of cardiometabolic
disease (CMD). However, individuals may develop CMD without traditional risk factors …
disease (CMD). However, individuals may develop CMD without traditional risk factors …
[HTML][HTML] Role of PAI-1 in hepatic steatosis and dyslipidemia
Abstract Plasminogen activator inhibitor 1 (PAI-1) is a functional biomarker of the metabolic
syndrome. Previous studies have demonstrated that PAI-1 is a mechanistic contributor to …
syndrome. Previous studies have demonstrated that PAI-1 is a mechanistic contributor to …
Associations of plasma proteomics with type 2 diabetes and related traits: results from the longitudinal KORA S4/F4/FF4 Study
Aims/hypothesis This study aimed to elucidate the aetiological role of plasma proteins in
glucose metabolism and type 2 diabetes development. Methods We measured 233 proteins …
glucose metabolism and type 2 diabetes development. Methods We measured 233 proteins …
Proteomic predictors of incident diabetes: results from the atherosclerosis risk in communities (ARIC) study
OBJECTIVE The plasma proteome preceding diabetes can improve our understanding of
diabetes pathogenesis. RESEARCH DESIGN AND METHODS In 8,923 Atherosclerosis Risk …
diabetes pathogenesis. RESEARCH DESIGN AND METHODS In 8,923 Atherosclerosis Risk …
Targeted Proteomics Reveals Functional Targets for Early Diabetes Susceptibility in Young Adults
BACKGROUND: The circulating proteome may encode early pathways of diabetes
susceptibility in young adults for surveillance and intervention. Here, we define proteomic …
susceptibility in young adults for surveillance and intervention. Here, we define proteomic …
[HTML][HTML] Longitudinal plasma protein profiling of newly diagnosed type 2 diabetes
Background Comprehensive proteomics profiling may offer new insights into the
dysregulated metabolic milieu of type 2 diabetes, and in the future, serve as a useful tool for …
dysregulated metabolic milieu of type 2 diabetes, and in the future, serve as a useful tool for …
Dietary pattern specific protein biomarkers for cardiovascular disease: a cross‐sectional study in 2 independent cohorts
E Warensjö Lemming, L Byberg, K Stattin… - Journal of the …, 2019 - Am Heart Assoc
Background Mechanisms related to the influence of diet on the development of
cardiovascular disease are not entirely understood, and protein biomarkers may help to …
cardiovascular disease are not entirely understood, and protein biomarkers may help to …
[HTML][HTML] Design of peptide ligand for lactoferrin and study of its binding specificity
The in silico modelling of peptides complementary to lactoferrin was carried out using the
Protein 3D software package and replication of the natural bonding site between …
Protein 3D software package and replication of the natural bonding site between …
[HTML][HTML] Plasma Galectin-4 levels are increased after stroke in mice and humans
A Jujic, JPP Vieira, H Matuskova, PM Nilsson… - International Journal of …, 2023 - mdpi.com
Epidemiological studies have associated plasma galectin-4 (Gal-4) levels with prevalent
and incident diabetes, and with an increased risk of coronary artery disease. To date, data …
and incident diabetes, and with an increased risk of coronary artery disease. To date, data …