[HTML][HTML] 3D cell culture systems: tumor application, advantages, and disadvantages
O Habanjar, M Diab-Assaf, F Caldefie-Chezet… - International journal of …, 2021 - mdpi.com
The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long
been used in cancer research. However, this system cannot be fully translated into clinical …
been used in cancer research. However, this system cannot be fully translated into clinical …
[HTML][HTML] Is it time to start transitioning from 2D to 3D cell culture?
Cell culture is an important and necessary process in drug discovery, cancer research, as
well as stem cell study. Most cells are currently cultured using two-dimensional (2D) …
well as stem cell study. Most cells are currently cultured using two-dimensional (2D) …
[HTML][HTML] Spheroids as a type of three-dimensional cell cultures—examples of methods of preparation and the most important application
K Białkowska, P Komorowski, M Bryszewska… - International journal of …, 2020 - mdpi.com
Cell cultures are very important for testing materials and drugs, and in the examination of
cell biology and special cell mechanisms. The most popular models of cell culture are two …
cell biology and special cell mechanisms. The most popular models of cell culture are two …
[HTML][HTML] Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration
Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …
attention as a way to better mimic the complex interactions between individual cells and the …
Microfluidic templated stem cell spheroid microneedles for diabetic wound treatment
Wound dressing patches based on stem cells have demonstrated promising potential in the
treatment of diabetic wounds, while their capabilities in the maintenance of cell stemness …
treatment of diabetic wounds, while their capabilities in the maintenance of cell stemness …
[PDF][PDF] Mechanical adaptability of tumor cells in metastasis
The most dangerous aspect of cancer lies in metastatic progression. Tumor cells will
successfully form life-threatening metastases when they undergo sequential steps along a …
successfully form life-threatening metastases when they undergo sequential steps along a …
m6A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells
S Huff, SK Tiwari, GM Gonzalez, Y Wang… - ACS Chemical …, 2021 - ACS Publications
N 6-methyladenosine (m6A) has emerged as the most abundant mRNA modification that
regulates gene expression in many physiological processes. m6A modification in RNA …
regulates gene expression in many physiological processes. m6A modification in RNA …
[HTML][HTML] Three-dimensional in vitro cell culture models for efficient drug discovery: Progress so far and future prospects
Despite tremendous advancements in technologies and resources, drug discovery still
remains a tedious and expensive process. Though most cells are cultured using 2D …
remains a tedious and expensive process. Though most cells are cultured using 2D …
[HTML][HTML] Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modeling
N Chaicharoenaudomrung, P Kunhorm… - World journal of stem …, 2019 - ncbi.nlm.nih.gov
Abstract Three-dimensional (3D) culture systems are becoming increasingly popular due to
their ability to mimic tissue-like structures more effectively than the monolayer cultures. In …
their ability to mimic tissue-like structures more effectively than the monolayer cultures. In …
Current updates and future perspectives on the management of renal cell carcinoma
D Singh - Life sciences, 2021 - Elsevier
Renal cell carcinoma (RCC) refers to renal-epithelial cancer, which represents over 90% of
kidney cancer and is a cause for cancer related deaths in the world. Studies suggested …
kidney cancer and is a cause for cancer related deaths in the world. Studies suggested …