Glomerulonephritis: immunopathogenesis and immunotherapy
Abstract 'Glomerulonephritis'(GN) is a term used to describe a group of heterogeneous
immune-mediated disorders characterized by inflammation of the filtration units of the kidney …
immune-mediated disorders characterized by inflammation of the filtration units of the kidney …
Membranous nephropathy: new pathogenic mechanisms and their clinical implications
E Hoxha, L Reinhard, RAK Stahl - Nature Reviews Nephrology, 2022 - nature.com
Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …
Insights into glomerular filtration and albuminuria
Glomerular Filtration and Albuminuria Chronic kidney diseases generally arise from a
disordered kidney filtration barrier within glomeruli. This review describes the roles of …
disordered kidney filtration barrier within glomeruli. This review describes the roles of …
New 'antigens' in membranous nephropathy
S Sethi - Journal of the American Society of Nephrology, 2021 - journals.lww.com
Membranous nephropathy (MN) occurs due to deposition of immune complexes along the
subepithelial region of glomerular basement membrane. Two previously identified target …
subepithelial region of glomerular basement membrane. Two previously identified target …
Rituximab or cyclophosphamide in the treatment of membranous nephropathy: the RI-CYCLO randomized trial
Background A cyclic corticosteroid-cyclophosphamide regimen is the first-line therapy for
membranous nephropathy. Compared with this regimen, rituximab therapy might have a …
membranous nephropathy. Compared with this regimen, rituximab therapy might have a …
Protocadherin 7–associated membranous nephropathy
Background Membranous nephropathy (MN) results from deposition of antigen-antibody
complexes along the glomerular basement membrane (GBM). PLA2R, THSD7A, NELL1 …
complexes along the glomerular basement membrane (GBM). PLA2R, THSD7A, NELL1 …
[HTML][HTML] Semaphorin 3B–associated membranous nephropathy is a distinct type of disease predominantly present in pediatric patients
S Sethi, H Debiec, B Madden, M Vivarelli… - Kidney international, 2020 - Elsevier
Membranous nephropathy results from subepithelial antigen-antibody complex deposition
along the glomerular basement membrane. Although PLA2R, THSD7A, and NELL-1 …
along the glomerular basement membrane. Although PLA2R, THSD7A, and NELL-1 …
[HTML][HTML] NELL1 is a target antigen in malignancy-associated membranous nephropathy
TN Caza, SI Hassen, Z Dvanajscak, M Kuperman… - Kidney international, 2021 - Elsevier
Patients with membranous nephropathy have an increased risk of malignancy compared to
the general population, but the target antigen for malignancy-associated membranous …
the general population, but the target antigen for malignancy-associated membranous …
Membranous nephropathy
P Ronco, L Beck, H Debiec, FC Fervenza… - Nature reviews Disease …, 2021 - nature.com
Membranous nephropathy (MN) is a glomerular disease that can occur at all ages. In adults,
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …
it is the most frequent cause of nephrotic syndrome. In~ 80% of patients, there is no …
Hematopoietic stem cell transplant-membranous nephropathy is associated with protocadherin FAT1
S Sethi, B Madden, MC Moura, SH Nasr… - Journal of the …, 2022 - journals.lww.com
Background Membranous nephropathy (MN) is a common cause of proteinuria in patients
receiving a hematopoietic stem cell transplant (HSCT). The target antigen in HSCT …
receiving a hematopoietic stem cell transplant (HSCT). The target antigen in HSCT …