The Nrd1–Nab3–Sen1 transcription termination complex from a structural perspective

B Chaves-Arquero… - Biochemical Society …, 2023 - portlandpress.com
A substantial part of living cells activity involves transcription regulation. The RNA
polymerases responsible for this job need to know 'where/when'to start and stop in the …

Nab3's localization to a nuclear granule in response to nutrient deprivation is determined by its essential prion-like domain

TJ Loya, TW O'Rourke, WC Simke, JB Kelley… - PLoS …, 2018 - journals.plos.org
Ribonucleoprotein (RNP) granules are higher order assemblies of RNA, RNA-binding
proteins, and other proteins, that regulate the transcriptome and protect RNAs from …

Characterization of the mechanisms of transcription termination by the helicase Sen1

O Porrua, D Libri - RNA Remodeling Proteins: Methods and Protocols, 2015 - Springer
In vitro transcription systems have been widely used to study all the steps of transcription
from initiation to termination and many transcription-coupled processes. Here we describe …

[HTML][HTML] Regulated chloroplast transcription termination

D Ji, N Manavski, J Meurer, L Zhang, W Chi - Biochimica et Biophysica Acta …, 2019 - Elsevier
Transcription termination by the RNA polymerase (RNAP) is a fundamental step of gene
expression that involves the release of the nascent transcript and dissociation of the RNAP …

Nucleoside triphosphate phosphohydrolase I (NPH I) functions as a 5′ to 3′ translocase in transcription termination of vaccinia early genes

R Hindman, P Gollnick - Journal of Biological Chemistry, 2016 - ASBMB
Vaccinia virus early genes are transcribed immediately upon infection. Nucleoside
triphosphate phosphohydrolase I (NPH I) is an essential component of the early gene …

Investigating transcription reinitiation through in vitro approaches

G Dieci, B Fermi, MC Bosio - Transcription, 2014 - Taylor & Francis
By influencing the number of RNA molecules repeatedly synthesized from the same gene,
the control of transcription reinitiation has the potential to shape the transcriptome …

Pathological R-loops in bacteria from engineered expression of endogenous antisense RNAs whose synthesis is ordinarily terminated by Rho

A Pandiyan, J Mallikarjun, H Maheshwari… - bioRxiv, 2024 - biorxiv.org
In many bacteria, the essential factors Rho and NusG mediate termination of synthesis of
nascent transcripts (including antisense RNAs) which are not being simultaneously …

DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts.

K Kus, L Carrique, T Kecman, M Fournier… - bioRxiv, 2023 - biorxiv.org
The timely termination of RNA polymerase II (Pol II) transcription is critical for polymerase
recycling and preventing interference with the expression of the neighbouring genes …

Helicases as transcription termination factors: Different solutions for a common problem

Z Han, O Porrua - Transcription, 2018 - Taylor & Francis
Helicases are enzymes that remodel nucleic acids or protein-nucleic acid complexes in an
ATP-dependent manner. They are ubiquitous and can play many diverse functions related to …

Does transcription play a role in creating a condensin binding site?

P Bernard, V Vanoosthuyse - Transcription, 2015 - Taylor & Francis
The highly conserved condensin complex is essential for the condensation and integrity of
chromosomes through cell division. Published data argue that high levels of transcription …