Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

During the last decade, the utilization of 68Ga for the development of imaging agents has
increased considerably with the leading position in the oncology. The imaging of infection …

Purpose Increased angiogenesis after myocardial infarction is considered an important
favorable prognostic parameter. The αvβ3 integrin is a key mediator of cell-cell and cell …

Nuclear imaging techniques can detect and quantify pathophysiological processes
underlying heart failure, complementing evaluation of cardiac structure and function with …

Advances in medical imaging technology have led to an increased demand for
radiopharmaceuticals for early and accurate diagnosis of cardiac function and diseased …

Cardiovascular diseases (CVD) is a collective term describing a range of conditions that
affect the heart and blood vessels. Due to the varied nature of the disorders, distinguishing …

Therapeutic angiogenesis induced by gene therapy is a promising approach to treat patients
suffering from severe coronary artery disease. In small experimental animals, adeno …

[68Ga] Ga-NODAGA-Arg-Gly-Asp (RGD) is a PET tracer targeting αvβ3 integrin, which is
upregulated during angiogenesis soon after acute myocardial infarction (AMI). We …

As therapeutic approaches have evolved from exogenous bone marrow cell delivery to
pharmacological stimulation of endogenous repair, so too has imaging of cardiac repair …

Introduction Non-invasive imaging techniques (especially single-photon emission
tomography and positron emission tomography) apply several RGD-based imaging ligands …