Abstract Surfactant Protein B (SP-B) deficiency has been recently identified as an
uncommon, autosomal recessive lung disorder in term infants. This inability to produce SP-B …

We report serial measurements of lung volume and airflow in small children after lung
transplantation. We expected that immature lungs could grow and develop normal volumes …

Background and objectives. Surfactant protein B deficiency has become increasingly
recognized as a cause of severe prolonged respiratory distress. Little has been written about …

Hereditary surfactant protein B (SP-B) deficiency is an autosomal recessive disease in which
affected infants are unable to produce normally functional surfactant, resulting in neonatal …

Pulmonary alveolar proteinosis (PAP) is characterized by the accumulation of surfactant
derived material in the lung of patients. PAP is rare in children. The patient presented with …

The treatment of interstitial lung disease in children depends on the nature of the underlying
pathology. In approximately 50% of cases a specific aetiology can be found such as: chronic …

Although genetic factors are assumed to have a role in the etiology of respiratory distress
syndrome (RDS), specific genes underlying this susceptibility are incompletely known. The …

Opinion statement Lung transplantation in children is an effective treatment for end-stage
pulmonary disease after all medical therapy has failed. It requires a huge investment in …

Aaron Hamvas, MD ulmonary surfactant is a complex mixture of p phospholipid and protein
that is synthesized--by alveolar type II pneumocytes and is necessary to maintain alveolar …

Pulmonary surfactant is a multimolecular complex located at the air-water interface within
the alveolus to which a range of physical (surface-active properties) and immune functions …