The activation of the pyrin inflammasome represents a highly intriguing mechanism
employed by the innate immune system to effectively counteract pathogenic agents. Despite …

Objective To evaluate the safety of canakinumab using real-world data in patients with
systemic juvenile idiopathic arthritis (sJIA) and autoinflammatory diseases (AID). Research …

The primary aim of this study was to document the treatment modalities used in periodic
fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome and look for the …

Abstract Familial Mediterranean Fever (FMF) is linked with the MEFV gene and is the
commonest among monogenic autoinflammatory diseases, with high prevalence in the …

Aim To determine the factors associated with colchicine resistance and the effect of
colchicine resistance on health‐related quality of life (QoL) in patients with familial …

Classical attacks of familial Mediterranean fever (FMF) are often accompanied by fever, but
some of the patients have attacks without fever. This study aimed to compare the …

Objectives The aim of this study was to investigate the clinical associations of the second
allele mutations and the effect of genotype and presenting features on colchicine resistance …

Background: The accruing evidence about the efficacy of anti-IL-1 agents in Familial
Mediterranean Fever (FMF) patients led to their widespread off-label use. Therefore …

Periodic fever syndromes (PFS) are a group of autoinflammatory diseases characterized by
repeated febrile episodes and systemic inflammation. The most common monogenic …

Aim The aim of this study was to investigate the frequency and type of FMF-associated
inflammatory diseases in a large FMF pediatric patients and to compare them to those FMF …