Sorting and export of proteins at the endoplasmic reticulum

I Raote, S Saxena, V Malhotra - Cold Spring Harbor …, 2023 - cshperspectives.cshlp.org
Secretory proteins are transported from the endoplasmic reticulum (ER) to the Golgi complex
in carriers that are formed by the concerted activities of cytoplasmic proteins in the coat …

Biogenesis and delivery of extracellular vesicles: harnessing the power of EVs for diagnostics and therapeutics

J Yu, S Sane, JE Kim, S Yun, HJ Kim, KB Jo… - Frontiers in Molecular …, 2024 - frontiersin.org
Extracellular vesicles (EVs) are membrane-enclosed particles secreted by a variety of cell
types. These vesicles encapsulate a diverse range of molecules, including proteins, nucleic …

O-GlcNAc Dynamics: The Sweet Side of Protein Trafficking Regulation in Mammalian Cells

A Ben Ahmed, Q Lemaire, J Scache, C Mariller… - Cells, 2023 - mdpi.com
The transport of proteins between the different cellular compartments and the cell surface is
governed by the secretory pathway. Alternatively, unconventional secretion pathways have …

COPII vesicles in plant autophagy and endomembrane trafficking

B Li, Y Zeng, L Jiang - FEBS letters, 2022 - Wiley Online Library
In eukaryotes, the endomembrane system allows for spatiotemporal compartmentation of
complicated cellular processes. The plant endomembrane system consists of the …

ER exit in physiology and disease

CM Robinson, A Duggan, A Forrester - Frontiers in Molecular …, 2024 - frontiersin.org
The biosynthetic secretory pathway is comprised of multiple steps, modifications and
interactions that form a highly precise pathway of protein trafficking and secretion, that is …

TFG regulates inner COPII coat recruitment to facilitate anterograde secretory protein transport

W Kasberg, P Luong, K Minushkin, I Pustova… - Molecular Biology of …, 2024 - molbiolcell.org
Coat protein complex II (COPII) governs the initial steps of biosynthetic secretory protein
transport from the endoplasmic reticulum (ER), facilitating the movement of a wide variety of …

PhyloString: A web server designed to identify, visualize, and evaluate functional relationships between orthologous protein groups across different phylogenetic …

C Dorantes-Torres, M Carrera-Reyna, W Santos… - Plos one, 2024 - journals.plos.org
Proteins are biological units whose essence is defined by their functional relationships with
other proteins or biomolecules such as RNA, DNA, lipids, or carbohydrates. These functions …

Knockdown of Sec16 causes early lethality and defective deposition of the protein Rp30 in the eggshell of the vector Rhodnius prolixus

T Rios, L Bomfim, J Pereira, K Miranda… - Frontiers in Cell and …, 2024 - frontiersin.org
In nearly every species of insect, embryonic development takes place outside of the mother's
body and is entirely dependent on the elements that the mother had previously stored within …

Fetal spina bifida associates with dysregulation in nutrient‐sensitive placental gene networks: Findings from a matched case–control study

M White, J Arif‐Pardy, T Van Mieghem… - Clinical and …, 2024 - Wiley Online Library
To improve outcomes in fetuses with spina bifida (SB), better understanding is needed of the
molecular drivers of SB and its comorbidities. Pregnant people carrying a fetus with isolated …

Sec16 and Sed4 interdependently function as interaction and localization partners at ER exit sites

T Yorimitsu, K Sato - Journal of Cell Science, 2023 - journals.biologists.com
ABSTRACT COPII proteins assemble at ER exit sites (ERES) to form transport carriers. The
initiation of COPII assembly in the yeast Saccharomyces cerevisiae is triggered by the ER …