The successful outcomes of chimeric antigen receptor (CAR) T-cell therapy in treating
hematologic cancers have increased the previously unprecedented excitement to use this …

Traditional cancer treatments use nonspecific drugs and monoclonal antibodies to target
tumor cells. Chimeric antigen receptor (CAR)-T cell therapy, however, leverages the immune …

Oncolytic viruses (OVs) infect, multiply, and finally remove tumor cells selectively, causing no
damage to normal cells in the process. Because of their specific features, such as, the ability …

Simple Summary Macrophages are the “big eaters” of the immune system who are in charge
of engulfing undesirable substances. Macrophages are vital for the human body as they are …

In recent years, the incidence of colorectal cancer (CRC) and breast cancer (BC) has
increased worldwide and caused a higher mortality rate due to the lack of selective anti …

T helper (Th) 17 cells are one of the most important T cell subsets in a number of
autoimmune and chronic inflammatory diseases. During infections, Th17 cells appear to …

Current genome-wide studies have indicated that a great number of long non-coding RNAs
(lncRNAs) are transcribed from the human genome and appeared as crucial regulators in a …

In the past decade, adoptive cell therapy with chimeric antigen receptor‐T (CAR‐T) cells has
revolutionized cancer treatment. However, the complexity and high costs involved in …

Altered branched chain amino acids (BCAAs), including leucine, isoleucine, and valine, are
frequently observed in patients with advanced cancer. We evaluated the efficacy of chimeric …

Over the past decade, there has been continuous advancement in immunotherapy to
improve human health. A promising technique that has emerged is chimeric antigen …