Regulatory T cells: the many faces of Foxp3
Regulatory T (Treg) cells expressing the transcription factor forkhead box P3 (Foxp3) play a
requisite role in the maintenance of immunological homeostasis and prevention of …
requisite role in the maintenance of immunological homeostasis and prevention of …
Treg cells in health and autoimmune diseases: New insights from single cell analysis
C Scheinecker, L Göschl, M Bonelli - Journal of autoimmunity, 2020 - Elsevier
Autoimmune diseases, such as Systemic Lupus Erythematosus (SLE) or Rheumatoid
Arthritis (RA) are characterized by the breakdown of immunological tolerance. Defects of …
Arthritis (RA) are characterized by the breakdown of immunological tolerance. Defects of …
Treg specialization and functions beyond immune suppression
JL Astarita, CX Dominguez, C Tan… - Clinical and …, 2023 - academic.oup.com
The actions of the immune system are finely tuned, involving complex communication and
coordination between diverse immune and non-immune cells across the tissues of the body …
coordination between diverse immune and non-immune cells across the tissues of the body …
[HTML][HTML] Clinical, immunological, and molecular heterogeneity of 173 patients with the phenotype of immune dysregulation, polyendocrinopathy, enteropathy, X-linked …
E Gambineri, S Ciullini Mannurita, D Hagin… - Frontiers in …, 2018 - frontiersin.org
Background: Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX)
Syndrome is a rare recessive disorder caused by mutations in the FOXP3 gene. In addition …
Syndrome is a rare recessive disorder caused by mutations in the FOXP3 gene. In addition …
An integrated taxonomy for monogenic inflammatory bowel disease
Background & aims Monogenic forms of inflammatory bowel disease (IBD) illustrate the
essential roles of individual genes in pathways and networks safeguarding immune …
essential roles of individual genes in pathways and networks safeguarding immune …
[HTML][HTML] Cellular and molecular mechanisms breaking immune tolerance in inborn errors of immunity
G Sogkas, F Atschekzei, IR Adriawan… - Cellular & Molecular …, 2021 - nature.com
In addition to susceptibility to infections, conventional primary immunodeficiency disorders
(PIDs) and inborn errors of immunity (IEI) can cause immune dysregulation, manifesting as …
(PIDs) and inborn errors of immunity (IEI) can cause immune dysregulation, manifesting as …
North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition position paper on the evaluation and management for patients with very early-onset …
JR Kelsen, KE Sullivan, S Rabizadeh… - Journal of pediatric …, 2020 - journals.lww.com
The rate of pediatric inflammatory bowel disease (IBD) has been increasing over the last
decade and this increase has occurred most rapidly in the youngest children diagnosed< 6 …
decade and this increase has occurred most rapidly in the youngest children diagnosed< 6 …
Clinical, immunological, and genetic features in patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-like syndrome
Background Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX)
syndrome is a rare inborn error of immunity caused by mutations in the forkhead box P3 …
syndrome is a rare inborn error of immunity caused by mutations in the forkhead box P3 …
Primary atopic disorders
JD Milner - Annual Review of Immunology, 2020 - annualreviews.org
Primary atopic disorders describes a series of monogenic diseases that have allergy-or
atopic effector–related symptoms as a substantial feature. The underlying pathogenic …
atopic effector–related symptoms as a substantial feature. The underlying pathogenic …