Amino acid transporters within the solute carrier superfamily: Underappreciated proteins and novel opportunities for cancer therapy
K Hushmandi, B Einollahi, SH Saadat, EHC Lee… - Molecular …, 2024 - Elsevier
Solute carrier (SLC), a diverse family of membrane proteins, are instrumental in
orchestrating the intake and efflux of nutrients including amino acids, vitamins, ions …
orchestrating the intake and efflux of nutrients including amino acids, vitamins, ions …
[HTML][HTML] A positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression
W Liu, Z Ding, Y Tao, S Liu… - Molecular …, 2024 - molecular-cancer.biomedcentral …
The aberrant expression of phosphofructokinase-platelet (PFKP) plays a crucial role in the
development of various human cancers by modifying diverse biological functions. However …
development of various human cancers by modifying diverse biological functions. However …
Nitidine chloride inhibits mTORC1 signaling through ATF4-mediated Sestrin2 induction and targets IGF2R for lysosomal degradation
F Chen, S Peng, C Li, F Yang, Y Yi, X Chen, H Xu… - Life Sciences, 2024 - Elsevier
Aims Nitidine chloride (NC), a natural phytochemical alkaloid derived from Zanthoxylum
nitidum (Roxb.) DC, exhibits multiple bioactivities, including antitumor, anti-inflammatory …
nitidum (Roxb.) DC, exhibits multiple bioactivities, including antitumor, anti-inflammatory …
Berberine ameliorates nonalcoholic fatty liver disease-induced bone loss by inhibiting ferroptosis
S Gu, J Wang, S Yu, S Zhang, T Gao, D Yan, R Xie… - Bone, 2024 - Elsevier
Background Nonalcoholic fatty liver disease (NAFLD) may contribute to osteoporosis.
Berberine is a traditional Chinese medicine and was recently shown to be beneficial in …
Berberine is a traditional Chinese medicine and was recently shown to be beneficial in …
Unlocking the Potential of Organoid Models in Ferroptosis: A Breakthrough in Cancer Research
D Lu, M Shu, Z Ma - Journal of Organoid and Bioscience, 2024 - jobs.isoor.org
Ferroptosis, a regulated form of cell death driven by iron-dependent lipid peroxidation, has
emerged as a critical mechanism in cancer biology. Understanding the molecular …
emerged as a critical mechanism in cancer biology. Understanding the molecular …