[HTML][HTML] Regulatory roles of histone modifications in filamentous fungal pathogens
Y Lai, L Wang, W Zheng, S Wang - Journal of Fungi, 2022 - mdpi.com
Filamentous fungal pathogens have evolved diverse strategies to infect a variety of hosts
including plants and insects. The dynamic infection process requires rapid and fine-tuning …
including plants and insects. The dynamic infection process requires rapid and fine-tuning …
[HTML][HTML] Mechanisms of Pulmonary Escape and Dissemination by Cryptococcus neoformans
Cryptococcus neoformans is a common environmental saprophyte and human fungal
pathogen that primarily causes disease in immunocompromised individuals. Similar to many …
pathogen that primarily causes disease in immunocompromised individuals. Similar to many …
[HTML][HTML] Gene Duplication Associated with Increased Fluconazole Tolerance in Candida auris cells of Advanced Generational Age
S Bhattacharya, T Holowka, EP Orner, BC Fries - Scientific reports, 2019 - nature.com
Candida auris is an emerging multi-drug resistant yeast that causes systemic infections.
Here we show that C. auris undergoes replicative aging (RA) that results from asymmetric …
Here we show that C. auris undergoes replicative aging (RA) that results from asymmetric …
[HTML][HTML] HDAC genes play distinct and redundant roles in Cryptococcus neoformans virulence
The human fungal pathogen Cryptococcus neoformans undergoes many phenotypic
changes to promote its survival in specific ecological niches and inside the host. To explore …
changes to promote its survival in specific ecological niches and inside the host. To explore …
[PDF][PDF] The role of ceramide synthases in the pathogenicity of Cryptococcus neoformans
Cryptococcus neoformans (C. neoformans) is estimated to cause about 220,000 new cases
every year in patients with AIDS, despite advances in antifungal treatments. C. neoformans …
every year in patients with AIDS, despite advances in antifungal treatments. C. neoformans …
[HTML][HTML] Systematic characterization of Ustilago maydis sirtuins shows Sir2 as a modulator of pathogenic gene expression
B Navarrete, JI Ibeas, RR Barrales - Frontiers in Microbiology, 2023 - frontiersin.org
Phytopathogenic fungi must adapt to the different environmental conditions found during
infection and avoid the immune response of the plant. For these adaptations, fungi must …
infection and avoid the immune response of the plant. For these adaptations, fungi must …
Sirtuins in epigenetic silencing and control of gene expression in model and pathogenic fungi
G Zhao, LN Rusche - Annual Review of Microbiology, 2022 - annualreviews.org
Fungi, including yeasts, molds, and mushrooms, proliferate on decaying matter and then
adopt quiescent forms once nutrients are depleted. This review explores how fungi use …
adopt quiescent forms once nutrients are depleted. This review explores how fungi use …
A fungal sirtuin modulates development and virulence in the insect pathogen, Beauveria bassiana
Q Cai, L Tian, JT Xie, QY Huang… - Environmental …, 2021 - Wiley Online Library
Chromatin transitions are mediated in part by acetylation/deacetylation post‐translational
modifications of histones. Histone deacetylases, eg sirtuins (Sir‐proteins), repress …
modifications of histones. Histone deacetylases, eg sirtuins (Sir‐proteins), repress …
[HTML][HTML] Replicative aging in pathogenic fungi
S Bhattacharya, T Bouklas, BC Fries - Journal of Fungi, 2020 - mdpi.com
Candida albicans, Candida auris, Candida glabrata, and Cryptococcus neoformans are
pathogenic yeasts which can cause systemic infections in immune-compromised as well as …
pathogenic yeasts which can cause systemic infections in immune-compromised as well as …
[HTML][HTML] Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host
T Bouklas, L Alonso-Crisóstomo, T Székely Jr… - PLoS …, 2017 - journals.plos.org
Similar to other yeasts, the human pathogen Candida glabrata ages when it undergoes
asymmetric, finite cell divisions, which determines its replicative lifespan. We sought to …
asymmetric, finite cell divisions, which determines its replicative lifespan. We sought to …