Biomarkers of sepsis: time for a reappraisal
Introduction Sepsis biomarkers can have important diagnostic, therapeutic, and prognostic
functions. In a previous review, we identified 3370 references reporting on 178 different …
functions. In a previous review, we identified 3370 references reporting on 178 different …
[HTML][HTML] Optimizing antibiotic therapies to reduce the risk of bacterial resistance
S Bassetti, S Tschudin-Sutter, A Egli… - European journal of …, 2022 - Elsevier
The incidence of infections caused by bacteria that are resistant to antibiotics is constantly
increasing. In Europe alone, it has been estimated that each year about 33′ 000 deaths are …
increasing. In Europe alone, it has been estimated that each year about 33′ 000 deaths are …
Procalcitonin (PCT)-guided antibiotic stewardship: an international experts consensus on optimized clinical use
P Schuetz, A Beishuizen, M Broyles… - Clinical Chemistry and …, 2019 - degruyter.com
Background Procalcitonin (PCT)-guided antibiotic stewardship (ABS) has been shown to
reduce antibiotics (ABxs), with lower side-effects and an improvement in clinical outcomes …
reduce antibiotics (ABxs), with lower side-effects and an improvement in clinical outcomes …
Procalcitonin to distinguish viral from bacterial pneumonia: a systematic review and meta-analysis
IS Kamat, V Ramachandran, H Eswaran… - Clinical Infectious …, 2020 - academic.oup.com
Because of the diverse etiologies of community-acquired pneumonia (CAP) and the
limitations of current diagnostic modalities, serum procalcitonin levels have been proposed …
limitations of current diagnostic modalities, serum procalcitonin levels have been proposed …
Procalcitonin: where are we now?
B Hamade, DT Huang - Critical Care Clinics, 2020 - criticalcare.theclinics.com
Procalcitonin (PCT) is a protein that consists of 116 amino acids and is the peptide precursor
of calcitonin. Calcitonin is initially biosynthesized as PCT, which, under normal conditions, is …
of calcitonin. Calcitonin is initially biosynthesized as PCT, which, under normal conditions, is …
Rationalizing antimicrobial therapy in the ICU: a narrative review
The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …
Procalcitonin to reduce long-term infection-associated adverse events in sepsis. A randomized trial
E Kyriazopoulou, L Liaskou-Antoniou… - American Journal of …, 2021 - atsjournals.org
Rationale: Although early antimicrobial discontinuation guided by procalcitonin (PCT) has
shown decreased antibiotic consumption in lower respiratory tract infections, the outcomes …
shown decreased antibiotic consumption in lower respiratory tract infections, the outcomes …
High procalcitonin levels associated with increased intensive care unit admission and mortality in patients with a COVID-19 infection in the emergency department
K Tong-Minh, Y van der Does, S Engelen… - BMC infectious …, 2022 - Springer
Background Patients with a severe COVID-19 infection often require admission at an
intensive care unit (ICU) when they develop acute respiratory distress syndrome (ARDS) …
intensive care unit (ICU) when they develop acute respiratory distress syndrome (ARDS) …
Biomarkers in pneumonia—beyond procalcitonin
M Karakioulaki, D Stolz - International journal of molecular sciences, 2019 - mdpi.com
Pneumonia is the leading infectious cause of mortality worldwide and one of the most
common lower respiratory tract infections that is contributing significantly to the burden of …
common lower respiratory tract infections that is contributing significantly to the burden of …
Point-of-care sensors for the management of sepsis
Point-of-care sensors that enable the fast collection of information relevant to a patient's
health state can facilitate improved health access, reduce healthcare costs and improve the …
health state can facilitate improved health access, reduce healthcare costs and improve the …