Introduction Sepsis biomarkers can have important diagnostic, therapeutic, and prognostic
functions. In a previous review, we identified 3370 references reporting on 178 different …

The incidence of infections caused by bacteria that are resistant to antibiotics is constantly
increasing. In Europe alone, it has been estimated that each year about 33′ 000 deaths are …

Background Procalcitonin (PCT)-guided antibiotic stewardship (ABS) has been shown to
reduce antibiotics (ABxs), with lower side-effects and an improvement in clinical outcomes …

Because of the diverse etiologies of community-acquired pneumonia (CAP) and the
limitations of current diagnostic modalities, serum procalcitonin levels have been proposed …

Procalcitonin (PCT) is a protein that consists of 116 amino acids and is the peptide precursor
of calcitonin. Calcitonin is initially biosynthesized as PCT, which, under normal conditions, is …

The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …

Rationale: Although early antimicrobial discontinuation guided by procalcitonin (PCT) has
shown decreased antibiotic consumption in lower respiratory tract infections, the outcomes …

Background Patients with a severe COVID-19 infection often require admission at an
intensive care unit (ICU) when they develop acute respiratory distress syndrome (ARDS) …

Pneumonia is the leading infectious cause of mortality worldwide and one of the most
common lower respiratory tract infections that is contributing significantly to the burden of …

Point-of-care sensors that enable the fast collection of information relevant to a patient's
health state can facilitate improved health access, reduce healthcare costs and improve the …