Clinical use of molecular data in thyroid nodules and cancer
AS Alzahrani - The Journal of Clinical Endocrinology & …, 2023 - academic.oup.com
Over the past 3 decades, advances in the molecular genetics of thyroid cancer (TC) have
been translated into diagnostic tests, prognostic markers, and therapeutic agents. The main …
been translated into diagnostic tests, prognostic markers, and therapeutic agents. The main …
Genomic and transcriptomic characteristics of metastatic thyroid cancers with exceptional responses to radioactive iodine therapy
Purpose: The determinants of response or resistance to radioiodine (RAI) are unknown. We
aimed to identify genomic and transcriptomic factors associated with structural responses to …
aimed to identify genomic and transcriptomic factors associated with structural responses to …
Clinical Implications of mTOR Expression in Papillary Thyroid Cancer—A Systematic Review
A Derwich, M Sykutera, B Bromińska, M Andrusiewicz… - Cancers, 2023 - mdpi.com
Simple Summary Papillary thyroid cancer (PTC) comprises approximately 80% of all thyroid
malignancies. The field of PTC genetics and cancerogenesis remains undetermined …
malignancies. The field of PTC genetics and cancerogenesis remains undetermined …
Disease-specific survival trends for patients presenting with differentiated thyroid cancer and distant metastases in the United States, 1992–2018
A Wilhelm, PC Conroy, L Calthorpe, AM Shui… - Thyroid, 2023 - liebertpub.com
Objective: Differentiated thyroid cancer (DTC) is associated with an excellent prognosis, but
patients with distant metastatic DTC have a 10-year disease-specific survival (DSS) of just …
patients with distant metastatic DTC have a 10-year disease-specific survival (DSS) of just …
Different Threshold of Malignancy for RAS-like Thyroid Tumors Causes Significant Differences in Thyroid Nodule Practice
K Kakudo - Cancers, 2022 - mdpi.com
Simple Summary Histopathological diagnosis is prone to significant observer variation in the
diagnosis of papillary thyroid carcinomas (PTCs) due to different thresholds of malignancy …
diagnosis of papillary thyroid carcinomas (PTCs) due to different thresholds of malignancy …
Molecular signature incorporating the immune microenvironment enhances thyroid cancer outcome prediction
Genomic and transcriptomic analysis has furthered our understanding of many tumors. Yet,
thyroid cancer management is largely guided by staging and histology, with few molecular …
thyroid cancer management is largely guided by staging and histology, with few molecular …
A Critical Assessment of Diagnostic Criteria for the Tall Cell Subtype of Papillary Thyroid Carcinoma—How Much? How Tall? And When Is It Relevant?
Tall cell papillary thyroid carcinoma (TC-PTC) is considered adverse histology. However,
previous studies are confounded by inconsistent criteria and strong associations with other …
previous studies are confounded by inconsistent criteria and strong associations with other …
Papillary thyroid carcinomas with tall cell features: an intermediate entity between classic and tall cell subtypes
A Bikas, K Wong, T Pappa, S Ahmadi, CB Wakefield… - Thyroid, 2023 - liebertpub.com
Background: While the diagnosis of papillary thyroid carcinomas (PTCs) with tall cell
features (PTCtcf) is often made for carcinomas with histological features intermediate …
features (PTCtcf) is often made for carcinomas with histological features intermediate …
Mutation in Genes Encoding Key Functional Groups Additively Increase Mortality in Patients with BRAFV600E-Mutant Advanced Papillary Thyroid Carcinoma
E Song, M Jin, A Jang, MJ Jeon, DE Song, HJ Yoo… - Cancers, 2021 - mdpi.com
Simple Summary The BRAFV600E point mutation is the most common driver mutation in
papillary thyroid carcinoma (PTC) and is known to be associated with aggressive clinical …
papillary thyroid carcinoma (PTC) and is known to be associated with aggressive clinical …
LncRNA ABHD11-AS1 promotes tumor progression in papillary thyroid carcinoma by regulating EPS15L1/EGFR signaling pathway
H Lu, C Zhu, Y Chen, Y Ruan, L Fan, Q Chen… - Clinical and Translational …, 2022 - Springer
Abstract Objectives lncRNA ABHD11 antisense RNA 1 (ABHD11-AS1) acts as an oncogene
involved in papillary thyroid carcinoma (PTC) occurrence and progression. ABHD11-AS1 …
involved in papillary thyroid carcinoma (PTC) occurrence and progression. ABHD11-AS1 …