Effect of amlodipine on systolic blood pressure

CB Levine, KR Fahrbach, D Frame, JE Connelly… - Clinical …, 2003 - Elsevier
Background: Systolic hypertension is the most common form of hypertension, particularly in
people aged> 60 years. Caused by decreased compliance of large arteries, systolic …

[HTML][HTML] Low-dose dextromethorphan, a NADPH oxidase inhibitor, reduces blood pressure and enhances vascular protection in experimental hypertension

TC Wu, CY Chao, SJ Lin, JW Chen - 2012 - journals.plos.org
Background Vascular oxidative stress may be increased with age and aggravate endothelial
dysfunction and vascular injury in hypertension. This study aimed to investigate the effects of …

[HTML][HTML] Комплаенс больных, получающих гипотензивную терапию

КГ Гуревич - Качественная клиническая практика, 2008 - clinvest.ru
Аннотация Термин'комплаенс'можно определить как соблюдение режима приема
лекарственного препарата пациентом. На комплаенс влияют как нежелательные …

Antihypertensive medication and quality of life—silent treatment of a silent killer?

AD Bremner - Cardiovascular drugs and therapy, 2002 - Springer
Hypertension is one of the major killers in the modern world and one of the great ironies of
the disease is that it has little or no immediate effect on affected individuals' quality of life …

Impact of compliance with oral antihyperglycemic agents on health outcomes in type 2 diabetes mellitus: a focus on frequency of administration

PJ Guillausseau - Treatments in endocrinology, 2005 - Springer
Compliance with treatment is crucial to the optimal management of any chronic disease.
Non-compliance with antihyperglycemic treatment is clearly a significant issue for patients …

Demonstration of safety in Alzheimer's patients for intervention with an anti‐hypertensive drug Nilvadipine: results from a 6‐week open label study

SP Kennelly, L Abdullah, D Paris… - … journal of geriatric …, 2011 - Wiley Online Library
Background Nilvadipine may lower rates of conversion from mild‐cognitive impairment to
Alzheimer's disease (AD), in hypertensive patients. However, it remains to be determined …

Development of pellets of nifedipine using HPMC K15 M and κ-carrageenan as mucoadhesive sustained delivery system and in vitro evaluation

PP Ige, P Rajput, C Pardeshi, R Kawade, B Swami… - Iranian Polymer …, 2013 - Springer
Polymeric mucoadhesive pellets of nifedipine were designed using computer software and
they were prepared by extrusion-spheronization using HPMC K15M and κ-carrageenan with …

What role do lay beliefs about hypertension etiology play in perceptions of medication effectiveness?

DL Frosch, S Kimmel, K Volpp - Health Psychology, 2008 - psycnet.apa.org
Background: Some people take the disease label" hypertension" literally; leading to the
belief that increasing relaxation instead of medication is the best treatment for this condition …

'Why don't you do as I tell you?'Compliance and antihypertensive regimens

L Hansson - International journal of clinical practice, 2002 - Wiley Online Library
Although hypertension is recognised as one of the major health hazards in the developed
world, compliance with antihypertensive regimens is still undesirably low This brings …

Sensitivity of estimands in clinical trials with imperfect compliance

H Chen, DF Heitjan - The international journal of biostatistics, 2024 - degruyter.com
In clinical trials that are subject to noncompliance, the commonly used intention-to-treat
estimand is valid as a causal effect of treatment assignment but is sensitive to the level of …