Molecular imaging of cancer with positron emission tomography

SS Gambhir - Nature Reviews Cancer, 2002 - nature.com
The imaging of specific molecular targets that are associated with cancer should allow
earlier diagnosis and better management of oncology patients. Positron emission …

Molecular imaging: exploring the next frontier

R Weissleder - Radiology, 1999 - pubs.rsna.org
The key elements (Fig 2) to sampling molecular information are (a) the use of special
imaging probes with high specificity,(b) appropriate amplification strategies, and (c) sensitive …

Feasibility of FDG imaging of the coronary arteries: comparison between acute coronary syndrome and stable angina

IS Rogers, K Nasir, AL Figueroa, RC Cury… - JACC: Cardiovascular …, 2010 - jacc.org
Objectives: This study tested the hypothesis that fluorodeoxyglucose (FDG) uptake within the
ascending aorta and left main coronary artery (LM), measured using positron emission …

Molecular imaging and its biological applications

ME Phelps - Eur J Nucl Med Mol Imaging, 2004 - Springer
This book is written as both a text and a reference book. It contains numerous images from
the biological sciences and clinical practice, tables, graphs, and fig ures, as well as …

Positron emission tomography scanning: current and future applications

J Czernin, ME Phelps - Annual review of medicine, 2002 - annualreviews.org
▪ Abstract Whole-body positron emission tomography (PET) imaging with 18F deoxyglucose
(FDG) is a molecular imaging modality that detects metabolic alterations in tumor cells that …

Results of preliminary clinical trials of the positron emission mammography system PEM-I: a dedicated breast imaging system producing glucose metabolic images …

K Murthy, M Aznar, CJ Thompson, A Loutfi… - Journal of Nuclear …, 2000 - Soc Nuclear Med
Early detection of breast cancer is crucial for efficient and effective treatment. We have
developed an instrument for positron emission mammography (PEM) called PEM-I that …

Impact of 18F-FDG PET on managing patients with colorectal cancer: the referring physician's perspective

J Meta, M Seltzer, C Schiepers… - Journal of nuclear …, 2001 - Soc Nuclear Med
Whole-body PET imaging with 18F-FDG has been used successfully to stage colorectal
cancer. However, the impact of FDG PET on patient management from the referring …

[HTML][HTML] Positron emission tomography with f18-fluorodeoxyglucose in the staging and preoperative evaluation of malignant pleural mesothelioma

DB Schneider, C Clary-Macy, S Challa… - The Journal of thoracic …, 2000 - Elsevier
Objectives: The purpose of this study was to evaluate the utility of positron emission
tomography with F18-fluorodeoxyglucose in the preoperative evaluation and staging of …

Positron emission tomography with computed tomography imaging of neuroinflammation in experimental autoimmune encephalomyelitis

CG Radu, CJ Shu, SM Shelly… - Proceedings of the …, 2007 - National Acad Sciences
2-[18F] Fluoro-2-deoxy-d-glucose positron emission tomography ([18F] FDG PET) detection
of the up-regulated glycolysis associated with malignant transformation is a noninvasive …

The role of functional and molecular imaging in cancer drug discovery and development

BM Seddon, P Workman - The British journal of radiology, 2003 - birpublications.org
Studies of pharmacokinetics (which is what the body does to the drug) and
pharmacodynamics (which is what the drug does to the body) are essential components of …