Thyroid carcinoma: phenotypic features, underlying biology and potential relevance for targeting therapy

J Hu, IJ Yuan, S Mirshahidi, A Simental, SC Lee… - International journal of …, 2021 - mdpi.com
Thyroid carcinoma consists a group of phenotypically heterogeneous cancers. Recent
advances in biological technologies have been advancing the delineation of genetic …

Machine intelligence in non-invasive endocrine cancer diagnostics

NM Thomasian, IR Kamel, HX Bai - Nature Reviews Endocrinology, 2022 - nature.com
Artificial intelligence (AI) has illuminated a clear path towards an evolving health-care
system replete with enhanced precision and computing capabilities. Medical imaging …

Ultrasound-guided radiofrequency ablation versus thyroid lobectomy for low-risk papillary thyroid microcarcinoma: a propensity-matched cohort study of 884 patients

L Yan, M Zhang, Q Song, Y Luo - Thyroid, 2021 - liebertpub.com
Background: Thermal ablation (TA) has been applied in patients with low-risk papillary
thyroid microcarcinoma (PTMC) who refuse surgery or active surveillance (AS). Recently, TA …

Multikinase inhibitors in thyroid cancer: timing of targeted therapy

ML Gild, VHM Tsang, RJ Clifton-Bligh… - Nature Reviews …, 2021 - nature.com
In the 9 years since the publication of our 2011 review of targeted treatment of thyroid cancer
with multikinase inhibitors, much has changed in the landscape of this heterogeneous …

Long-term outcomes of radiofrequency ablation for unifocal low-risk papillary thyroid microcarcinoma: a large cohort study of 414 patients

L Yan, Y Lan, J Xiao, L Lin, B Jiang, Y Luo - European Radiology, 2021 - Springer
Objectives The purpose of this study was to evaluate the long-term efficacy and safety of
radiofrequency ablation (RFA) for low-risk papillary thyroid microcarcinoma (PTMC) in a …

The role of thyroglobulin in preoperative and postoperative evaluation of patients with differentiated thyroid cancer

S Li, C Ren, Y Gong, F Ye, Y Tang, J Xu… - Frontiers in …, 2022 - frontiersin.org
Thyroglobulin (Tg) is secreted by thyroid follicular cells and stored in the thyroid follicular
lumen as a component of thyroid hormone. It is known that both benign and well …

[HTML][HTML] SERS assisted sandwich immunoassay platforms for ultrasensitive and selective detection of human Thyroglobulin

S Spaziani, G Quero, S Managò, G Zito… - Biosensors and …, 2023 - Elsevier
We developed an immunoassay platform for the detection of human Thyroglobulin (Tg) to be
integrated with fine-needle aspiration biopsy for early detection of lymph node metastases in …

Novel inhibitor-based therapies for thyroid cancer—An update

M Ratajczak, D Gaweł, M Godlewska - International journal of molecular …, 2021 - mdpi.com
Thyroid cancers (TCs) are the most common tumors of the endocrine system and a constant
rise in the number of TC cases has been observed for the past few decades. TCs are one of …

Mutational profiling of poorly differentiated and anaplastic thyroid carcinoma by the use of targeted next‐generation sequencing

H Duan, Y Li, P Hu, J Gao, J Ying, W Xu… - …, 2019 - Wiley Online Library
Aims To characterise the mutational profiles of poorly differentiated thyroid carcinoma
(PDTC) and anaplastic thyroid carcinoma (ATC) and to identify markers with potential …

[HTML][HTML] The BRAF V600E mutation is a predictor of the effect of radioiodine therapy in papillary thyroid cancer

J Ge, J Wang, H Wang, X Jiang, Q Liao, Q Gong… - Journal of …, 2020 - ncbi.nlm.nih.gov
Objective: To investigate the correlation between the BRAF V600E gene mutation and
clinicopathological features and thyroid function after iodine-131 treatment in patients with …