[HTML][HTML] An overview on the antibacterial properties of juglone, naphthazarin, plumbagin and lawsone derivatives and their metal complexes

C Majdi, V Duvauchelle, P Meffre… - Biomedicine & …, 2023 - Elsevier
Bacterial resistance development represents a serious threat to human health across the
globe and has become a very serious clinical problem for many classes of antibiotics …

Design, synthesis, spectroscopic characterization, single crystal X-ray analysis, in vitro α-amylase inhibition assay, DPPH free radical evaluation and computational …

M Devi, P Kumar, R Singh, J Sindhu… - European Journal of …, 2023 - Elsevier
In our quest to design and develop N/O-containing inhibitors of α-amylase, we have tried to
synergize the inhibitory action of 1, 4-naphthoquinone, imidazole and 1, 2, 3-triazole motifs …

New naphthoquinone thiazole hybrids as carbonic anhydrase and cholinesterase inhibitors: Synthesis, crystal structure, molecular docking, and acid dissociation …

C Efeoglu, O Selcuk, B Demir, E Sahin, H Sari… - Journal of Molecular …, 2024 - Elsevier
Abstract In this study, N-[3-(3-amino-1, 4-dioxo-1, 4-dihydronaphthalen-2-yl)-4-R-thiazol-2
(3H)-ylidene]-2, 6-difluorobenzamide derivatives as new 1, 4-naphthoquinone thiazole …

Anti‐inflammatory Potential of 1, 4‐Naphthoquinone Acyl Thiourea Hybrids on Lipopolysaccharide‐Activated Mammalian Macrophages, and Their Acid Dissociation …

C Canatar, H Türkben, C Efeoglu, H Sari… - …, 2023 - Wiley Online Library
In this study, seven new and known 1, 4‐naphthoquinone acyl thiourea hybrids were
synthesized and their molecular structures were confirmed by various analytical methods …

[HTML][HTML] Hybrids of 1, 4-Naphthoquinone with Thymidine Derivatives: Synthesis, Anticancer Activity, and Molecular Docking Study

M Kadela-Tomanek, K Krzykawski, A Halama… - Molecules, 2023 - mdpi.com
One of the most essential health problems is cancer, the first or second cause of death
worldwide. Head and neck cancers are hard to detect due to non-specific symptoms. The …

Synthesis of water-soluble novel bioactive pyridine-based azo coumarin derivative and competitive cytotoxicity, DNA binding, BSA binding study, and in silico analysis …

P Karan, B Shit, P Panja, A Khatun, J Pal… - Bioorganic …, 2023 - Elsevier
The diazo coupliling reaction of 3-amino pyridine with coumarin in water medium produces
water soluble 6-[3-pyridyl] azocoumarin. The synthesised compound has been fully …

[HTML][HTML] KuQuinones: a ten years tale of the new pentacyclic quinoid compound

F Valentini, F Sabuzi, M Forchetta, V Conte, P Galloni - RSC advances, 2023 - pubs.rsc.org
Quinones are widespread in nature, as they participate, mainly as redox mediators, in
several biochemical processes. Up to now, various synthetic quinones have been …

Design, synthesis, and evaluation of 1, 4-naphthoquinone-chromene hybrids as potential anti-K562 and A549 agents

WH Zhang, B Zhang, BW Pan, XW Liu, ZG Yin… - New Journal of …, 2024 - pubs.rsc.org
Two series of 1, 4-naphthoquinone-chromone hybrids 4a (4aa–4ao) and 4b (4ba–4bq) were
designed, synthesized and evaluated as antitumor agents. Most of the compounds exhibited …

Novel chalcone scaffolds of benzothiophene as an efficient real time hydrazine sensor: Synthesis and single crystal XRD studies

SN Tandel, P Mistry, PN Patel - Journal of Molecular Structure, 2023 - Elsevier
Continue to our on-going research, this article demonstrate the design and development of
an efficient real time hydrazine sensor. A series of novel chalcone scaffolds are synthesised …

Synthesis, Enzyme Inhibition, and Acid Dissociation Constant of 1, 4-Naphthoquinone Thiazole Hybrid

Y Nural, Y Demir - Hacettepe University Journal of the Faculty of …, 2024 - dergipark.org.tr
Bu çalışmada, yeni naftokinon tiyazol hibriti 3 1-((3r, 5r, 7r)-adamantan-1-il)-2-bromoetan-1-
on ile naftokinon açil tiyoüre bileşiğinin 2 tepkimesi ile 74% verimle sentezlendi ve …