Direct reconstruction methods have been developed to estimate parametric images directly
from the measured PET sinograms by combining the PET imaging model and tracer kinetics …

Objectives 18F-fluorodeoxyglucose (FDG) PET/CT has been widely used in tumor
diagnosis, staging, and response evaluation. To determine an optimal therapeutic strategy …

Purpose Ankylosing spondylitis (AS) is a chronic inflammatory disease of the axial spine;
however, the quantitative detection of inflammation in AS remains a challenge in clinical …

The P2X7 receptor (P2X7R) is a key neuroinflammation target in a variety of
neurodegenerative diseases. Improved radiosynthesis was developed according to the …

The present study aimed to evaluate the feasibility of ultra-low 18F-FDG activity in total-body
PET/CT oncologic studies. Methods: Thirty patients with cancer were enrolled prospectively …

Objectives Commercialized total-body PET scanners can provide high-quality images due to
its ultra-high sensitivity. We compared the dynamic, regular static, and delayed 18F …

Macrophages are a double-edged sword with potential cancer-promoting and anticancer
effects. Controversy remains regarding the effect of macrophages, especially M1 …

In the past decades, translocator protein (TSPO) has been considered as an in vivo
biomarker to measure the presence of neuroinflammatory reactions. In this study, expression …

Lymph node micro-metastasis (LNMM) was previously reported to be significantly correlated
with recurrence of lung cancer [1]. Conventional whole-body PET/CT has limited specificity …

The present study aimed to evaluate the feasibility of ultra-low 18 F-fluorodeoxyglucose
(FDG) activity in total-body positron emission tomography (PET)/computed tomography (CT) …