Platelets have a crucial role in haemostasis and atherothrombosis. Pharmacological control
of platelet hyper-reactivity has become a cornerstone in the prevention of thrombo …

Anticoagulant macromolecules have gained widespread use in the clinical treatment of
cardiovascular diseases, blood-contacting or implantable materials, and medical devices …

During fibrosis,(myo) fibroblasts deposit large amounts of extracellular matrix proteins,
thereby replacing healthy functional tissue. In liver fibrosis, this leads to the loss of …

Abstract Cyclooxygenase (COX) isozymes, ie, COX-1 and COX-2, are encoded by separate
genes and are involved in the generation of the same products, prostaglandin (PG) G 2 and …

Antithrombotic therapy is a delicate balance between the benefits of preventing a thrombotic
event and the risks of inducing a major bleed. Traditional approaches have included …

A gyulladás az egyik legősibb és egyben a leggyakrabban kialakuló kórfolyamat, amely
számos betegség patofiziológiai alapját képezi. A gyulladás nem más, mint a szervezet …