Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective …
The HER2-positive patients occupy~ 30% of the total breast cancer patients globally where
no prevalent drugs are available to mitigate the frequent metastasis clinically except …
no prevalent drugs are available to mitigate the frequent metastasis clinically except …
Multi-epitope vaccine for monkeypox using pan-genome and reverse vaccinology approaches
Outbreaks of monkeypox virus infections have imposed major health concerns worldwide,
with high morbidity threats to children and immunocompromised adults. Although …
with high morbidity threats to children and immunocompromised adults. Although …
FN1 and cancer‐associated fibroblasts markers influence immune microenvironment in clear cell renal cell carcinoma
Background Altered tumor microenvironment (TME) is characterized in clear cell renal cell
carcinoma (ccRCC) as a result of the heterogeneity observed in the TME. Modulations in …
carcinoma (ccRCC) as a result of the heterogeneity observed in the TME. Modulations in …
Translational protein RpsE as an alternative target for novel nucleoside analogues to treat MDR Enterobacter cloacae ATCC 13047: network analysis and molecular …
The pathogenic Enterobacter cloacae subsp. cloacae str. ATCC 13047 has contemporarily
emerged as a multi-drug resistant strain. To formulate an effective treatment option …
emerged as a multi-drug resistant strain. To formulate an effective treatment option …
WGS-based screening of the co-chaperone protein DjlA-induced curved DNA binding protein A (CbpA) from a new multidrug-resistant zoonotic mastitis-causing …
The research aimed to establish a multidrug-resistant Klebsiella pneumoniae-induced
genetic model for mastitis considering the alternative mechanisms of the DjlA-mediated …
genetic model for mastitis considering the alternative mechanisms of the DjlA-mediated …
A hypothetical model of multi-layered cost-effective wastewater treatment plant integrating microbial fuel cell and nanofiltration technology: a comprehensive review on …
Wastewater management has emerged as an uprising concern that demands immediate
attention from environmentalists worldwide. Indiscriminate and irrational release of industrial …
attention from environmentalists worldwide. Indiscriminate and irrational release of industrial …
Consolidated knowledge-guided computational pipeline for therapeutic intervention against bacterial biofilms-a review
Biofilm-associated bacterial infections attributed to multifactorial antimicrobial resistance
have caused worldwide challenges in formulating successful treatment strategies. In search …
have caused worldwide challenges in formulating successful treatment strategies. In search …
Discovery of small molecule PARKIN activator from antipsychotic/anti-neuropsychiatric drugs as therapeutics for PD: an in silico repurposing approach
A Ibrahim, N Ipinloju, NH Atasie, RM Babalola… - Applied biochemistry …, 2023 - Springer
Although there is presently no cure for Parkinson's disease (PD), the available therapies are
only able to lessen symptoms and preserve the quality of life. Around 10 million people …
only able to lessen symptoms and preserve the quality of life. Around 10 million people …
Differential gene expression analysis combined with molecular dynamics simulation study to elucidate the novel potential biomarker involved in pulmonary TB
S Panchalingam, G Kasivelu, M Jayaraman… - Microbial …, 2023 - Elsevier
Tuberculosis (TB) is a lethal multisystem disease that attacks the lungs' first line of defense.
A substantial threat to public health and a primary cause of death is pulmonary TB. This …
A substantial threat to public health and a primary cause of death is pulmonary TB. This …
Emergence of sulphonamide resistance in azithromycin-resistant pediatric strains of Salmonella Typhi and Paratyphi A: a genomics insight
Whole genome sequences of Salmonella enterica subspecies enterica serovar Typhi (S.
Typhi) and Salmonella enterica subspecies enterica serovar Paratyphi A (S. Paratyphi A) …
Typhi) and Salmonella enterica subspecies enterica serovar Paratyphi A (S. Paratyphi A) …