Enhancing cancer immunotherapeutic efficacy with sonotheranostic strategies

A Zafar, M Hasan, T Tariq, Z Dai - Bioconjugate Chemistry, 2021 - ACS Publications
Immunotherapy has revolutionized the modality for establishing a firm immune response
and immunological memory. However, intrinsic limitations of conventional low responsive …

Identification of ultra-rare genetic variants in pediatric acute onset neuropsychiatric syndrome (PANS) by exome and whole genome sequencing

R Trifiletti, HM Lachman, O Manusama, D Zheng… - Scientific reports, 2022 - nature.com
Abrupt onset of severe neuropsychiatric symptoms including obsessive–compulsive
disorder, tics, anxiety, mood swings, irritability, and restricted eating is described in children …

Transcryptomic analysis of human brain-microvascular endothelial response to-pericytes: cell orientation defines barrier function

L Kurmann, M Okoniewski, OO Ogunshola, B Leeners… - Cells, 2021 - mdpi.com
Pericytes facilitate blood–brain barrier (BBB) integrity; however, the mechanisms involved
remain unclear. Hence, using co-cultures of human cerebral microvascular endothelial cells …

Neurological complications associated with Covid‐19; molecular mechanisms and therapeutic approaches

M Mahboubi Mehrabani, MS Karvandi… - Reviews in medical …, 2022 - Wiley Online Library
With the progression of investigations on the pathogenesis of severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), neurological complications have emerged as a …

A peek into Pandora's box: COVID-19 and neurodegeneration

A Chandra, A Johri - Brain Sciences, 2022 - mdpi.com
Ever since it was first reported in Wuhan, China, the coronavirus-induced disease of 2019
(COVID-19) has become an enigma of sorts with ever expanding reports of direct and …

Immune mechanism of epileptogenesis and related therapeutic strategies

MJ Aguilar-Castillo, P Cabezudo-García… - Biomedicines, 2022 - mdpi.com
Immunologic and neuroinflammatory pathways have been found to play a major role in the
pathogenesis of many neurological disorders such as epilepsy, proposing the use of novel …

[HTML][HTML] Cerebral microvascular complications associated with SARS-CoV-2 infection: How did it occur and how should it be treated?

N Omidian, P Mohammadi, M Sadeghalvad… - Biomedicine & …, 2022 - Elsevier
Cerebral microvascular disease has been reported as a central feature of the neurological
disorders in patients with SARS-CoV-2 infection that may be associated with an increased …

[HTML][HTML] Molecular mechanisms of palmitic acid augmentation in COVID-19 pathologies

C Joshi, V Jadeja, H Zhou - International Journal of Molecular Sciences, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has claimed over 2.7 million lives
globally. Obesity has been associated with increased severity and mortality of COVID-19 …

Polystyrene microplastics exacerbate systemic inflammation in high-fat diet-induced obesity

AG Lee, S Kang, HJ Yoon, S Im, SJ Oh… - International Journal of …, 2023 - mdpi.com
Microplastics (MPs) are recognized as environmental pollutants with potential implications
for human health. Considering the rapid increase in obesity rates despite stable caloric …

Curcumin-pretreated adipose-derived stem cells enhance the neuroprotective ability to repair rheumatoid arthritis-induced damage in the rat brain

DT Ju, BCK Tsai, MA Sitorus, WW Kuo… - The American journal …, 2022 - World Scientific
Neurodegenerative diseases have become increasingly prevalent in the aged population.
Rheumatoid arthritis (RA) is an autoimmune disease that causes systemic inflammation …