Erythrocyte membrane fatty acid composition as a potential biomarker for depression

T Liu, L Wang, J Guo, T Zhao, H Tang… - International Journal …, 2023 - academic.oup.com
Background Major depressive disorders is a chronic and severe psychiatric disorder with
poor prognosis and quality of life. Abnormal erythrocyte fatty acid (FA) composition in …

[HTML][HTML] Thinking outside the black box: are the brain endothelial cells the new main target in Alzheimer's disease?

E Estudillo, A López-Ornelas… - Neural Regeneration …, 2023 - journals.lww.com
The blood-brain barrier is the interface through which the brain interacts with the milieu and
consists mainly of a sophisticated network of brain endothelial cells that forms blood vessels …

[HTML][HTML] Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration

AP Garza, L Morton, É Pállinger, EI Buzás… - Brain, behavior, & …, 2023 - Elsevier
Tobacco smoking is strongly linked to vascular damage contributing to the development of
hypertension, atherosclerosis, as well as increasing the risk for neurodegeneration. Still, the …

Dysfunction of ABC transporters at the surface of BBB: potential implications in intractable epilepsy and applications of nanotechnology enabled drug delivery

R Mohi-ud-Din, RH Mir, PA Mir, N Banday… - Current Drug …, 2022 - ingentaconnect.com
Epilepsy is a chronic neurological disorder affecting 70 million people globally. One of the
fascinating attributes of brain microvasculature is the (BBB), which controls a chain of distinct …

Sesamol Mitigates Chronic Iron Overload‐Induced Cognitive Impairment and Systemic Inflammation via IL‐6 and DMT1 Regulation

Y Wang, Y Zhang, X Wang, Q Li, Y Zhao… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope Excessive iron contributes to oxidative damage and cognitive decline in Alzheimer's
disease. Sesamol, a compound in sesame oil that exhibits both anti‐inflammatory and …

[HTML][HTML] Dose-Effect Determination of a Neuroprotector Fraction Standardized in Coumarins of Tagetes lucida and Bioavailability

A Santibáñez, M Herrera-Ruiz, M González-Cortazar… - Pharmaceutics, 2023 - mdpi.com
Neurodegeneration has been associated with chronic inflammation states in the brain. For
this reason, attention has been directed to drugs indicated as anti-inflammatory as possible …

Impact of SARS-CoV-2 on the nervous system

A Czarnowska, J Zajkowska… - … i Neurochirurgia Polska, 2023 - journals.viamedica.pl
Introduction. The ongoing COVID-19 pandemic is the largest global public health struggle.
The spread of the novel coronavirus had resulted in almost 7 million deaths worldwide by …

[HTML][HTML] Silver nanoparticles impair cognitive functions and modify the hippocampal level of neurotransmitters in a coating-dependent manner

K Dziendzikowska, M Węsierska… - International Journal of …, 2021 - mdpi.com
Due to their potent antibacterial properties, silver nanoparticles (AgNPs) are widely used in
industry and medicine. However, they can cross the brain–blood barrier, posing a risk to the …

[HTML][HTML] COVID-19 and Multiple Sclerosis: A Complex Relationship Possibly Aggravated by Low Vitamin D Levels

WD Fernandes de Souza, DM Fonseca, A Sartori - Cells, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an exceptionally
transmissible and pathogenic coronavirus that appeared at the end of 2019 and triggered a …

[HTML][HTML] Pharmacokinetic study of intranasal dexamethasone and methylprednisolone compared with intravenous administration: two open-label, single-dose, two …

G Cárdenas, RJ Bobes, G Fragoso, NI Pérez-Osorio… - Pharmaceutics, 2022 - mdpi.com
Dexamethasone (DXM) and methylprednisolone (MEP) are potent glucocorticoids used to
control several inflammatory conditions. Evidence of delayed DXM reaching the central …