The success of hematopoietic stem cell transplantation (HSCT) lies with the ability of the
engrafting immune system to remove residual leukemia cells via a graft-versus-leukemia …

MHC class I molecules are peptide receptors of stringent specificity which however still allow
millions of different ligands. This is achieved by the following specificity characteristics …

Background The human leucocyte antigen (HLA) complex controls adaptive immunity by
presenting defined fractions of the intracellular and extracellular protein content to immune …

The central unit for regulation of the specific immune system is a trimolecular complex made
up of the T cell antigen receptor, the MHC molecule, and the MHC ligand. The third …

The human leukocyte antigen (HLA) complex regulates the adaptive immune response by
showcasing the intracellular and extracellular protein content to the immune system, where …

Allogeneic stem cell transplantation is a form of immunotherapy that has increased the
chances of survival for patients with relapsed leukemia and high risk leukemia in remission …

ABSTRACT PA28γ is a proteasomal interactor whose main and most known function is to
stimulate the hydrolytic activity of the 20S proteasome independently of ubiquitin and ATP …

Over the past two decades, immunotherapy has become the fourth pillar in cancer treatment
alongside surgery, radiotherapy, and chemotherapy. Immune checkpoint blockade shows …

Актуальность темы: В течение последних десятилетий отмечается прогрессирующий
рост урогекитальных инфекций (УГИ)[Прилепская ВН и соавт., 2004; Шубин СВ., 2008; …

Any account of progress in the area of antigen processing and presentation is necessarily a
story of the past few years. In 1987, when Bjorkman, Wiley and their colleagues solved the …