Manganese-induced parkinsonism: evidence from epidemiological and experimental studies

R Lucchini, K Tieu - Biomolecules, 2023 - mdpi.com
Manganese (Mn) exposure has evolved from acute, high-level exposure causing
manganism to low, chronic lifetime exposure. In this latter scenario, the target areas extend …

[HTML][HTML] Role of p53 methylation in manganese-induced cyclooxygenase-2 expression in BV2 microglial cells

X Liu, C Yao, Y Tang, X Liu, C Duan, C Wang… - Ecotoxicology and …, 2022 - Elsevier
Manganese (Mn) is an essential cofactor for many enzymes and plays an important role in
normal growth and development. However, excess exposure to manganese (Mn) may be an …

Loss of slc39a14 causes simultaneous manganese hypersensitivity and deficiency in zebrafish

K Tuschl, RJ White, C Trivedi… - Disease Models & …, 2022 - journals.biologists.com
Manganese neurotoxicity is a hallmark of hypermanganesemia with dystonia 2, an inherited
manganese transporter defect caused by mutations in SLC39A14. To identify novel potential …

[HTML][HTML] Case Report: Childhood Erythrocytosis due to Hypermanganesemia Caused by Homozygous SLC30A10 Mutation

T Coppola, H Hughes, P Finch, J Hess, SW Wu… - Frontiers in …, 2024 - frontiersin.org
We present a rare case of erythrocytosis due to a homozygous SLC30A10 mutation,
causative of Hypermanganesemia with Dystonia, Polycythemia, and Cirrhosis (HMDPC) …