Bacteriophage delivery systems for food applications: Opportunities and perspectives

MJ Costa, LM Pastrana, JA Teixeira, SM Sillankorva… - Viruses, 2023 - mdpi.com
Currently, one-third of all food produced worldwide is wasted or lost, and bacterial
contamination is one of the main reasons. Moreover, foodborne diseases are a severe …

Efficacy of phage-and bacteriocin-based therapies in combatting nosocomial MRSA infections

L Walsh, CN Johnson, C Hill, RP Ross - Frontiers in molecular …, 2021 - frontiersin.org
Staphylococcus aureus is a pathogen commonly found in nosocomial environments where
infections can easily spread-especially given the reduced immune response of patients and …

Efficient synthesis of CRISPR-Cas13a-antimicrobial capsids against MRSA facilitated by silent mutation incorporation

Y Shimamori, XE Tan, FY Li, Y Nishikawa… - Scientific reports, 2024 - nature.com
In response to the escalating global threat of antimicrobial resistance, our laboratory has
established a phagemid packaging system for the generation of CRISPR-Cas13a …

Genetic engineering and biosynthesis technology: Keys to unlocking the chains of phage therapy

S Lv, Y Wang, K Jiang, X Guo, J Zhang, F Zhou, Q Li… - Viruses, 2023 - mdpi.com
Phages possess the ability to selectively eliminate pathogenic bacteria by recognizing
bacterial surface receptors. Since their discovery, phages have been recognized for their …

Bacteriophage therapy as an application for bacterial infection in China

S Liang, Y Qi, H Yu, W Sun, SHA Raza, N Alkhorayef… - Antibiotics, 2023 - mdpi.com
Antibiotic resistance has emerged as a significant issue to be resolved around the world.
Bacteriophage (phage), in contrast to antibiotics, can only kill the target bacteria with no …

Phage therapy: an alternative treatment modality for MDR bacterial infections

N Pal, P Sharma, M Kumawat, S Singh… - Infectious …, 2024 - Taylor & Francis
The increasing global incidence of multidrug-resistant (MDR) bacterial infections threatens
public health and compromises various aspects of modern medicine. Recognising the …

Environmental DNA transformation resulted in an active phage in Escherichia coli

A Karaynir, B Bozdoğan, H Salih Doğan - Plos one, 2023 - journals.plos.org
The achievement of an active biological entity from environmental DNA is important in the
field of phage. In this study, the environmental DNA extracted from hospital wastewater was …

More's the same—multiple hosts do not select for broader host range phages

J Myers, J Davis II, M Lollo, G Hudec, P Hyman - Viruses, 2023 - mdpi.com
Bacteriophage host range is a result of the interactions between phages and their hosts. For
phage therapy, phages with a broader host range are desired so that a phage can infect and …

Current Knowledge and Perspectives of Phage Therapy for Combating Refractory Wound Infections

B Wang, L Du, B Dong, E Kou, L Wang… - International Journal of …, 2024 - mdpi.com
Wound infection is one of the most important factors affecting wound healing, so its effective
control is critical to promote the process of wound healing. However, with the increasing …

Alginate- and Chitosan-Modified Gelatin Hydrogel Microbeads for Delivery of E. coli Phages

F Moghtader, S Solakoglu, E Piskin - Gels, 2024 - mdpi.com
Bacterial infections are among the most significant health problems/concerns worldwide. A
very critical concern is the rapidly increasing number of antibiotic-resistant bacteria, which …