Research into the molecular genetics of osteoarthritis (OA) has been substantially bolstered
in the past few years by the implementation of powerful genome-wide scans that have …

Articular chondrocytes are quiescent, fully differentiated cells responsible for the
homeostasis of adult articular cartilage by maintaining cellular survival functions and the fine …

Objective Osteoarthritis (OA) is the most prevalent joint disease. As disease-modifying
therapies are not available, novel therapeutic targets need to be discovered and prioritized …

Osteoarthritis (OA) has a very high incidence worldwide and has become a very common
joint disease in the elderly. Currently, the treatment methods for OA include surgery, drug …

Although osteoarthritis (OA) aetiology is complex, genetic, genomic and epigenetic studies
published within the last decade have advanced our understanding of the molecular …

The purpose of this narrative review is to provide an overview of last year's publications in
the field of genetics, genomics and epigenetics in the osteoarthritis (OA) field. Major themes …

Objectives Osteoarthritis (OA) is the most common degenerative joint disease in aged
population and its development is significantly influenced by aberrant epigenetic …

Osteoarthritis (OA) is the most common cause of disability worldwide among the elderly.
Alarmingly, the incidence of OA in individuals less than 40 years of age is rising, likely due to …

Phenotypic variation in skeletal traits and diseases is the product of genetic and
environmental factors. Epigenetic mechanisms include information‐containing factors, other …

Osteoarthritis is one of the most frequent and disabling diseases of the elderly. Only few
genetic variants have been identified for osteoarthritis, which is partly due to large …