Population pharmacokinetics and clinical response for artemether-lumefantrine in pregnant and nonpregnant women with uncomplicated Plasmodium falciparum …
Artemether-lumefantrine (AL) is the first-line treatment for uncomplicated malaria in the
second and third trimesters of pregnancy. Its efficacy during pregnancy has recently been …
second and third trimesters of pregnancy. Its efficacy during pregnancy has recently been …
Pharmacokinetic properties of artemether, dihydroartemisinin, lumefantrine, and quinine in pregnant women with uncomplicated Plasmodium falciparum malaria in …
Pregnancy alters the pharmacokinetic properties of many drugs used in the treatment of
malaria, usually resulting in lower drug exposures. This increases the risks of treatment …
malaria, usually resulting in lower drug exposures. This increases the risks of treatment …
Intermittent preventive treatment with dihydroartemisinin-piperaquine for the prevention of malaria among HIV-infected pregnant women
P Natureeba, A Kakuru, M Muhindo… - The Journal of …, 2017 - academic.oup.com
Background. Daily trimethoprim-sulfamethoxazole (TMP-SMX) and insecticide-treated nets
remain the main interventions for prevention of malaria in human immunodeficiency virus …
remain the main interventions for prevention of malaria in human immunodeficiency virus …
[HTML][HTML] Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort
D Mosha, F Mazuguni, S Mrema, E Sevene, S Abdulla… - Malaria journal, 2014 - Springer
Background There is limited data available regarding safety profile of artemisinins in early
pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for …
pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for …
[HTML][HTML] The safety of artemisinin derivatives for the treatment of malaria in the 2nd or 3rd trimester of pregnancy: a systematic review and meta-analysis
Given the high morbidity for mother and fetus associated with malaria in pregnancy, safe
and efficacious drugs are needed for treatment. Artemisinin derivatives are the most effective …
and efficacious drugs are needed for treatment. Artemisinin derivatives are the most effective …
Artemisinin-Based Combination Therapy Versus Quinine or Other Combinations for Treatment of Uncomplicated Plasmodium falciparum Malaria in the Second and …
RJ Burger, AM van Eijk, M Bussink, J Hill… - Open forum …, 2016 - academic.oup.com
Abstract The World Health Organization recommends artemisinin-based combination
therapies (ACTs) for the treatment of uncomplicated falciparum malaria in the second and …
therapies (ACTs) for the treatment of uncomplicated falciparum malaria in the second and …
[HTML][HTML] The Use of Artemether-Lumefantrine for the Treatment of Uncomplicated Plasmodium vivax Malaria
Q Bassat - PLoS Neglected Tropical Diseases, 2011 - journals.plos.org
The long-standing dearth of knowledge surrounding Plasmodium vivax, the most widely
distributed of the malaria species, merits urgent attention. A growing awareness of the true …
distributed of the malaria species, merits urgent attention. A growing awareness of the true …
Lumefantrine and desbutyl-lumefantrine population pharmacokinetic-pharmacodynamic relationships in pregnant women with uncomplicated Plasmodium falciparum …
F Kloprogge, R McGready… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Artemether-lumefantrine is the most widely used antimalarial artemisinin-based combination
treatment. Recent studies have suggested that day 7 plasma concentrations of the potent …
treatment. Recent studies have suggested that day 7 plasma concentrations of the potent …
Artemether-lumefantrine pharmacokinetics and clinical response are minimally altered in pregnant Ugandan women treated for uncomplicated falciparum malaria
Artemether-lumefantrine is a first-line regimen for the treatment of uncomplicated malaria
during the second and third trimesters of pregnancy. Previous studies have reported …
during the second and third trimesters of pregnancy. Previous studies have reported …
[HTML][HTML] Timing of malaria in pregnancy and impact on infant growth and morbidity: a cohort study in Uganda
P De Beaudrap, E Turyakira, C Nabasumba… - Malaria journal, 2016 - Springer
Abstract Background Malaria in pregnancy (MiP) is a major cause of fetal growth restriction
and low birth weight in endemic areas of sub-Saharan Africa. Understanding of the impact of …
and low birth weight in endemic areas of sub-Saharan Africa. Understanding of the impact of …