Copper is an indispensable micronutrient for the development and replication of all
eukaryotes, and its redox properties are both harmful and beneficial to cells. An imbalance …

The Janus kinase (JAK) signal transducer and activator of transcription (JAK-STAT) pathway
is an evolutionarily conserved mechanism of transmembrane signal transduction that …

Background Lung cancer is a significant health concern in China. There is limited available
data of its burden and trends. This study aims to evaluate the trends of lung cancer across …

Gastrointestinal (GI) cancer is a formidable malignancy with significant morbidity and
mortality rates. Recent studies have shed light on the complex interplay between the …

To develop a potential theranostic metal agent to reverse the resistance of cancer cells to
cisplatin and effectively inhibit tumor growth and metastasis, we proposed to design a …

Background We analysed the cancer burden among elderly Chinese people over the age of
55 years and compared them to USA and Western Europe to explore the cancer model in …

Background In this study, we aimed to investigate the performance of GALAD, GALAD-C,
and GAAP models in Chinese population in comparison to our newly build statistical model …

Six-transmembrane epithelial antigen of the prostate 3 (STEAP3) has been reported to play
a regulatory role in various types of cancers. However, its involvement in lung squamous cell …

Background: Dendritic cells (DCs) are the most important antigen-presenting cells in the
body and play a key role in antigen recognition, uptake, processing, and presentation and …

Abstract Background Circulating tumor cells (CTCs) hold immense promise in guiding
treatment strategies for advanced gastric cancer (GC). However, their clinical impact has …